Gold nanoparticle based signal enhancement liquid crystal biosensors for DNA hybridization assays

被引：67
|
作者：
Yang, Shengyuan [1 ,2 ]
Liu, Yanmei [1 ]
Tan, Hui [1 ]
Wu, Chao [1 ]
Wu, Zhaoyang [1 ]
Shen, Guoli [1 ]
Yu, Ruqin [1 ]
机构：
[1] Hunan Univ, Coll Chem & Chem Engn, State Key Lab Chemo Biosensing & Chemometr, Changsha 410082, Hunan, Peoples R China
[2] Univ S China, Coll Publ Hlth, Hengyang 421001, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2012年 / 48卷 / 23期
基金：
中国国家自然科学基金;
关键词：
BOVINE SERUM-ALBUMIN; SOLID-SURFACES; AMPLIFICATION; TRANSITIONS; PROTEINS; PROBES; FILMS; QUANTIFICATION; ORIENTATIONS; ELECTRODES;
D O I：
10.1039/c2cc17861c
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A novel signal enhanced liquid crystal biosensor based on using AuNPs for highly sensitive DNA detection has been developed. This biosensor not only significantly decreases the detection limit, but also offers a simple detection process and shows a good selectivity to distinguish perfectly matched target DNA from two-base mismatched DNA.
引用
收藏
页码：2861 / 2863
页数：3
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