Altered fractionated radiotherapy in the management of head and neck carcinomas: advantages and limitations

被引:24
|
作者
Bourhis, J
Etessami, A
Wilbault, P
Lusinchi, A
Calais, G
Lapeyre, M
Pignon, JP
机构
[1] Inst Gustave Roussy, Dept Radiat Oncol, F-94805 Villejuif, France
[2] Inst Gustave Roussy, Dept Stat, F-94805 Villejuif, France
[3] CHU Tours, Clin Oncol & Radiotherapie, Tours, France
[4] Ctr Alexis Vautrin, Nancy, France
关键词
head and neck squamous cell carcinoma; hyperfractionation; accelerated radiotherapy; acute and late effects;
D O I
10.1097/00001622-200405000-00004
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Purpose of review This article provides an overview of randomized studies of altered fractionated radiotherapy (RT) in Head and Neck squamous cell carcinoma. Recent findings Both hyperfractionated RT and accelerated RT may improve tumor control probability as compared to conventional RT, along with increased but manageable toxicity and a modest improvement in survival. Summary Altered RT is a tool that can improve the results obtained with conventional RT in Head and squamous cell carcinoma.
引用
收藏
页码:215 / 219
页数:5
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