An expedient protocol of the Biginelli dihydropyrimidine synthesis using carbonyl equivalents

被引：95
|
作者：
Singh, K
Singh, J
Deb, PK
Singh, H [1 ]
机构：
[1] Guru Nanak Dev Univ, Dept Appl Chem Sci & Technol, Amritsar 143005, Punjab, India
[2] Guru Nanak Dev Univ, Dept Chem, Amritsar 143005, Punjab, India
来源：
TETRAHEDRON | 1999年 / 55卷 / 44期
关键词：
D O I：
10.1016/S0040-4020(99)00760-7
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A one - pot condensation of perhydro-1,3 heterocycles - aldehyde equivalents with ethyl acetoacetate and ureas provides a convenient synthesis of the title compounds with a variety of substituents at C-4. Yields are equivalent or significantly higher than the conventional methods. (C) 1999 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：12873 / 12880
页数：8
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