In vivo T-cell depletion with antithymocyte globulin or alemtuzumab for unrelated donor stem cell transplantation with reduced intensity conditioning: results of a multicentre randomized phase II clinical trial (the Global study) from the GITMO

被引:0
|
作者
Algarotti, A. [1 ]
Mico, C. [1 ]
Corradini, P. [2 ]
Falda, M. [3 ]
Alessandrino, E. P. [4 ]
Fanin, R. [5 ]
Tagliaferri, E. [6 ]
Castagna, L. [7 ]
Mordini, N. [8 ]
Sica, S. [9 ]
Santarone, S. [10 ]
Levis, A. [11 ]
Iori, A. [12 ]
Pollichieni, S. [13 ]
Sacchi, N. [13 ]
Scarano, M. [14 ]
Masciulli, A. [14 ]
Marchioli, R. [14 ]
Bacigalupo, A. [15 ]
Bosi, A. [16 ]
Rambaldi, A. [1 ]
机构
[1] Osped Papa Giovanni XXIII, Bergamo, Italy
[2] Ist Nazl Tumori, I-20133 Milan, Italy
[3] Osped San Giovanni Battista Torino, Turin, Italy
[4] Policlin San Matteo, I-27100 Pavia, Italy
[5] AO Univ Udine, Udine, Italy
[6] Osped Maggiore Policlin, Milan, Italy
[7] Ist Clin Humanitas, Milan, Italy
[8] AO Santa Croce & Carle, Cuneo, Italy
[9] Policlin Gemelli, Rome, Italy
[10] Osped Civile, Pescara, Italy
[11] AO SS Antonio & Biagio & C Arrigo, Alessandria, Italy
[12] Univ Roma La Sapienza, Rome, Italy
[13] Osped Galliera, Genoa, Italy
[14] Ist Mario Negri Sud, Santa Maria Imbaro, Italy
[15] Osped San Martino Genova, Genoa, Italy
[16] Osped Careggi, Florence, Italy
关键词
D O I
暂无
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
引用
收藏
页码:S60 / S61
页数:2
相关论文
共 50 条
  • [21] Impact of CD8+ T-cell dose on GvhD after antithymocyte globulin (ATG)-based reduced-intensity conditioning (RIC) for allogeneic stem cell transplantation
    Mohty, M
    Faucher, C
    Bagattini, S
    Bardou, V
    Bilger, K
    Gaugler, B
    Chabannon, C
    Ladaique, P
    Lemarie, C
    Vey, N
    Gastaut, JA
    Maraninchi, D
    Olive, D
    Blaise, D
    BONE MARROW TRANSPLANTATION, 2004, 33 : S181 - S181
  • [22] The role of in vivo T-cell depletion on reduced-intensity conditioning allogeneic stem cell transplantation from HLA-identical siblings in patients with follicular lymphoma
    Delgado, J.
    Canals, C.
    Attal, M.
    Thomson, K.
    Campos, A.
    Martino, R.
    Littlewood, T.
    Jackson, G.
    Milpied, N.
    Boogaerts, M.
    Hunter, A.
    Janssen, J. J. W. M.
    Montoto, S.
    Sureda, A.
    LEUKEMIA, 2011, 25 (03) : 551 - 555
  • [23] The role of in vivo T-cell depletion on reduced-intensity conditioning allogeneic stem cell transplantation from HLA-identical siblings in patients with follicular lymphoma
    J Delgado
    C Canals
    M Attal
    K Thomson
    A Campos
    R Martino
    T Littlewood
    G Jackson
    N Milpied
    M Boogaerts
    A Hunter
    J J W M Janssen
    S Montoto
    A Sureda
    Leukemia, 2011, 25 : 551 - 555
  • [24] The pattern of T-cell donor chimerism is a key predictor of outcome following alemtuzumab based reduced intensity conditioning hematopoietic stem cell transplantation for MDS and AML.
    Lim, ZiYi
    Pearce, Laurence
    Ho, Aloysius Y. L.
    Barber, Linda
    Ingram, Wendy
    Usai, Monica
    Devereux, Stephen
    Pagliuca, Antonio
    Mufti, Ghulam
    BLOOD, 2006, 108 (11) : 17A - 17A
  • [25] Comparative analysis of melphalan versus busulphan T-cell deplete conditioning using alemtuzumab in unrelated donor stem cell transplantation for acute myeloid leukaemia
    Sellar, Rob S.
    Mehra, Varun
    Fox, Thomas A.
    Grigg, Andrew
    Kulasekararaj, Austin
    Sarma, Anita
    de Lavallade, Hugues
    McLornan, Donal
    Raj, Kavita
    Mufti, Ghulam J.
    Pagliuca, Antonio
    Mackinnon, Stephen
    Chakraverty, Ronjon
    Fielding, Adele K.
    Carpenter, Ben
    Kottaridis, Panagiotis D.
    Khwaja, Asim
    Peggs, Karl S.
    Thomson, Kirsty J.
    Morris, Emma C.
    Potter, Victoria T.
    BRITISH JOURNAL OF HAEMATOLOGY, 2019, 187 (01) : E20 - E24
  • [26] Reduced-intensity stem cell transplantation for adult T-Cell leukemia: The results of a second multi-center prospective study and the impact of antithymocyte globulin on early relapse.
    Uike, Naokuni
    Tanosaki, Ryuji
    Utsunomiya, Atae
    Choi, Ilseung
    Masuda, Masato
    Saburi, Yoshio
    Tomonaga, Masao
    Etoh, Tetsuya
    Hidaka, Michihiro
    Kannagi, Mari
    Harada, Mine
    Okamura, Jun
    BLOOD, 2006, 108 (11) : 432B - 433B
  • [27] Unrelated stem cell transplantation in multiple myeloma after a reduced-intensity conditioning with pretransplantation antithymocyte globulin is highly effective with low transplantation-related mortality
    Kröger, N
    Sayer, HG
    Schwerdtfeger, R
    Kiehl, M
    Nagler, A
    Renges, H
    Zabelina, T
    Fehse, B
    Ayuk, F
    Wittkowsky, G
    Schmitz, N
    Zander, AR
    BLOOD, 2002, 100 (12) : 3919 - 3924
  • [28] T-cell depletion does not necessarily compromise donor stem cell engraftment in patients receiving reduced-intensity conditioning regimens
    Craddock, C
    Grigg, AP
    BONE MARROW TRANSPLANTATION, 2003, 31 (12) : 1177 - 1177
  • [29] Predictive factors and impact of full donor T-cell chimerism after reduced intensity conditioning allogeneic stem cell transplantation
    Eliaou, J. F.
    Mohty, M.
    Avinens, O.
    Faucher, C.
    Viens, P.
    Vey, N.
    Blaise, D.
    TISSUE ANTIGENS, 2006, 67 (06): : 485 - 486
  • [30] Predictive factors and impact of full donor T-cell chimerism after reduced intensity conditioning allogeneic stem cell transplantation
    Mohty, Mohamad
    Avinens, Odile
    Faucher, Catherine
    Viens, Patrice
    Blaise, Didier
    Eliaou, Jean-Francois
    HAEMATOLOGICA, 2007, 92 (07) : 1004 - 1006