Copper-Catalyzed Cascade Phosphorylation Initiated Radical Cyclization: Access to 2-Phosphorylated Pyrrolo[1,2-a]indole

被引：62

作者：

Zhang, Honglin ^{[1
]}

Li, Weipeng ^{[1
]}

Zhu, Chengjian ^{[1
,2
]}

机构：

[1] Nanjing Univ, Sch Chem & Chem Engn, State Key Lab Coordinat Chem, Jiangsu Key Lab Adv Organ Mat, Nanjing 210093, Jiangsu, Peoples R China

[2] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2017年 / 82卷 / 04期

基金：

中国国家自然科学基金;

关键词：

CARBON-PHOSPHORUS FUNCTIONALIZATION; OXIDATIVE CYCLIZATION; BOND; DERIVATIVES; ALKENES; 2-ISOCYANOBIPHENYLS; ACTIVATION; INHIBITORS; OXIDES;

D O I：

10.1021/acs.joc.6b02673

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A copper-catalyzed tandem radical cyclization of 1-(3-phenylprop-2-yn-1-yl)-1H-indole with diphenylphosphine oxides was developed. CP bond formation was achieved coupled with C(sp(2))H functionalization. It provided an access to construct the pyrrolo[1,2-a]indole motif and a series of 2-phosphinoyl-9H-pyrrolo[1,2-a]indoles.

引用

页码：2199 / 2204

页数：6

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