Use of computer-based case studies in a problem-solving curriculum

In this article we discuss the use of computers in the teaching of physical chemistry in the PharmD curriculum, in a problem-solving oriented course based on the performance of case studies by groups of students. The purpose of the course is both to increase the computer literacy of students, while at the same time educating them in critical thinking and problem-solving in areas relevant to pharmaceutical formulation and delivery. We will discuss three computer-based case studies which address the kinetics of drug degradation, the flocculation of dispersed systems and the sequestration of drugs via binding to albumin. In answering these case studies, students were expected to use MS-Windows, Excel spreadsheets, e-mail, molecular graphics, word processing, on-line literature searching and other computer-based techniques. The emphasis on computation was motivated by the changing role of the pharmacist, and the need for pharmacy graduates to effectively compete with other professionals in the job market. We believe that individuals who possess effective computer skills, strong foundations in fundamental pharmaceutical concepts, and an ability to problem-solve will be able to make contributions in many areas, and will have the flexibility to respond to a changing professional environment.