Solubility of Pravastatin Sodium in Water, Methanol, Ethanol, 2-Propanol, 1-Propanol, and 1-Butanol from (278 to 333) K

被引：4

作者：

Jia, Chunyan ^{[1
]}

Yin, Qiuxiang ^{[1
]}

Song, Jingling ^{[1
]}

Hou, Guangyang ^{[1
]}

Zhang, Meijing ^{[1
]}

机构：

[1] Tianjin Univ, Sch Chem Engn & Technol, Tianjin 300072, Peoples R China

来源：

JOURNAL OF CHEMICAL AND ENGINEERING DATA | 2008年 / 53卷 / 10期

关键词：

D O I：

10.1021/je800196k

中图分类号：

O414.1 [热力学];

学科分类号：

摘要：

The solubilities of pravastatin sodium in water, methanol, ethanol, 2-propanol, 1-propanol, and 1-butanol from (278 to 333) K were measured. A laser monitoring observation technique was used to determine the dissolution of the solid phase in the solid + liquid mixture. The experimental data were correlated with a semiempirical equation. The solubilities in the six solvents decrease in the following order: water > methanol > ethanol > 1-propanol > 1-butanol > 2-propanol.

引用

页码：2466 / 2468

页数：3

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