Mcl-1: the 1 in CLL

被引：23
|
作者：
Gandhi, Varsha [1 ]
Balakrishnan, Kumudha [1 ]
Chen, Lisa S. [1 ]
机构：
[1] Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USA
来源：
BLOOD | 2008年 / 112卷 / 09期
关键词：
D O I：
10.1182/blood-2008-07-170241
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Although Mcl-1 has been established as a survival and maintenance protein during in vitro incubations of primary CLL cells, in this issue of Blood, Pepper and colleagues further demonstrate the association of Mcl-1 with other prognostic factors and the role of this antiapoptotic protein in disease progression and outcome for patients with CLL.
引用
收藏
页码：3538 / 3540
页数：5
相关论文
共 50 条
  • [41] Modeling the Binding of Anticancer Peptides and Mcl-1
    Alhammadi, Shamsa Husain Ahmed
    Baby, Bincy
    Antony, Priya
    Jobe, Amie
    Humaid, Raghad Salman Mohammed
    Alhammadi, Fatema Jumaa Ahmed
    Vijayan, Ranjit
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2024, 25 (12)
  • [42] Role of MCL-1 in cytokine signaling pathway
    Chao, JR
    Yang-Yen, HF
    EUROPEAN CYTOKINE NETWORK, 1998, 9 (03) : 308 - 308
  • [43] Apoptotic Regulation by MCL-1 through Heterodimerization
    Liu, Qian
    Moldoveanu, Tudor
    Sprules, Tara
    Matta-Camacho, Edna
    Mansur-Azzam, Nura
    Gehring, Kalle
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2010, 285 (25) : 19615 - 19624
  • [44] Development of Mcl-1 inhibitors for cancer therapy
    Negi, Arvind
    Murphy, Paul, V
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 210
  • [45] Mcl-1 reduction: releasing a death brake?
    Sayers, TJ
    BLOOD, 2005, 105 (08) : 3005 - 3005
  • [46] MCL-1 keeps a charming home for thymocytes
    Tai, Xuguang
    BLOOD, 2017, 130 (23) : 2448 - 2450
  • [47] Functional analysis of the human MCL-1 gene
    C. Akgul
    P. C. Turner
    M. R. H. White
    S. W. Edwards*
    Cellular and Molecular Life Sciences CMLS, 2000, 57 : 684 - 691
  • [48] Mcl-1 is a key regulator of the ovarian reserve
    S Omari
    M Waters
    T Naranian
    K Kim
    A L Perumalsamy
    M Chi
    E Greenblatt
    K H Moley
    J T Opferman
    A Jurisicova
    Cell Death & Disease, 2015, 6 : e1755 - e1755
  • [49] Hot-Spots of Mcl-1 Protein
    Denis, Camille
    Santos, Jana Sopkova-de Oliveira
    Bureau, Ronan
    Voisin-Chiret, Anne Sophie
    JOURNAL OF MEDICINAL CHEMISTRY, 2020, 63 (03) : 928 - 943
  • [50] Mcl-1 is essential for the survival of plasma cells
    Peperzak, Victor
    Vikstroem, Ingela
    Walker, Jennifer
    Glaser, Stefan P.
    LePage, Melanie
    Coquery, Christine M.
    Erickson, Loren D.
    Fairfax, Kirsten
    Mackay, Fabienne
    Strasser, Andreas
    Nutt, Stephen L.
    Tarlinton, David M.
    NATURE IMMUNOLOGY, 2013, 14 (03) : 290 - 297
12345