Evaluation of different methods to determine the loading of proteins in PLGA microspheres

被引：0
|
作者：
Zheng, CH [1 ]
Liang, WQ [1 ]
Yu, HY [1 ]
Chen, HL [1 ]
机构：
[1] Zhejiang Univ, Coll Pharmaceut Sci, Dept Pharmaceut, Hangzhou 310031, Peoples R China
来源：
PHARMAZIE | 2004年 / 59卷 / 03期
关键词：
D O I：
暂无
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Various determination methods for protein encapsulation efficiency of PLGA microspheres were compared. Acetonitrile is recommended as an extraction solvent.
引用
收藏
页码：232 / 233
页数：2
相关论文
共 50 条
  • [21] Factors affecting the loading efficiency of water-soluble drugs in PLGA microspheres
    Ito, Fuminori
    Fujimori, Hiroyuki
    Makino, Kimiko
    COLLOIDS AND SURFACES B-BIOINTERFACES, 2008, 61 (01) : 25 - 29
  • [22] FTIR characterization of the secondary structure of proteins encapsulated within PLGA microspheres'
    Fu, K
    Griebenow, K
    Hsieh, L
    Klibanov, AM
    Langer, R
    JOURNAL OF CONTROLLED RELEASE, 1999, 58 (03) : 357 - 366
  • [23] Preparation of novel ropivacaine hydrochloride-loaded PLGA microspheres based on post-loading mode and efficacy evaluation
    Wen, Kang
    Na, Xiangming
    Yuan, Miaomiao
    Bazybek, Nardana
    Li, Xun
    Wei, Yi
    Ma, Guanghui
    COLLOIDS AND SURFACES B-BIOINTERFACES, 2022, 210
  • [24] Studies of in vitro Evaluation and Formulation of Aceclofenac Loaded PLGA Microspheres
    Gupta, V.
    Shukla, S. K.
    Shrivastava, S. M.
    Shukla, S.
    Kumar, K.
    Saxena, D. P.
    Shrivastava, B.
    Chaudhary, M.
    INTERNATIONAL JOURNAL OF PHARMACOLOGY, 2010, 6 (05) : 726 - 731
  • [25] Studies on the preparation, characterization and pharmacological evaluation of tolterodine PLGA microspheres
    Sun, Fengying
    Sui, Cheng
    Teng, Lesheng
    Liu, Ximing
    Teng, Lirong
    Meng, Qingfan
    Li, Youxin
    INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2010, 397 (1-2) : 44 - 49
  • [26] Preparation and in vivo evaluation of huperzine A-loaded PLGA microspheres
    Fu, XD
    Gao, YL
    Ping, QN
    Ren, T
    ARCHIVES OF PHARMACAL RESEARCH, 2005, 28 (09) : 1092 - 1096
  • [27] Preparation and in vivo evaluation of thienorphine-loaded PLGA microspheres
    Yang, Yang
    Gao, Yongliang
    PHARMAZIE, 2010, 65 (10): : 729 - 732
  • [28] Preparation and In Vitro Performance Evaluation of Ellagic Acid PLGA Microspheres
    Qin, Shu-Zhi
    Ling, Wen-Pei
    Liang, Jun-Yu
    Li, Zhang-Xian
    Chen, Xiao-Tong
    Liu, Jia-Jie
    Teng, Li-Rong
    BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2020, 126 : 19 - 19
  • [29] Evaluation of the paromomycin loading characteristics in nanoprecipitated PLGA nanospheres
    Kalimouttou, S.
    Lahiani-Skiba, M.
    Naouli, N.
    Lin, V. Shengzhao
    Skiba, M.
    NSTI NANOTECH 2008, VOL 2, TECHNICAL PROCEEDINGS: LIFE SCIENCES, MEDICINE, AND BIO MATERIALS, 2008, : 407 - +
  • [30] Evaluation of different methods to determine heavy metal fractions present in the soil
    Martinez, Yadira
    Rivero, Carmen
    INGENIERIA UC, 2005, 12 (03): : 14 - 20
12345