Idiopathic CD4 Lymphocytopenia (HIV-Negative AIDS): Case Report and Literature Review

被引：0

作者：

Aksoy, Firdevs ^{[1
]}

Aydin, Murat ^{[1
]}

Yilmaz, Gurdal ^{[1
]}

Guvercin, Ali Riza ^{[2
]}

Eyuboglu, Ilker ^{[3
]}

Sari, Ahmet ^{[3
]}

Bayramoglu, Gulcin ^{[4
]}

Koksal, Iftihar ^{[1
]}

机构：

[1] Karadeniz Tech Univ, Dept Infect Dis & Clin Microbiol, Fac Med, Trabzon, Turkey

[2] Karadeniz Tech Univ, Dept Neurosurg, Fac Med, Trabzon, Turkey

[3] Karadeniz Tech Univ, Dept Radiol, Fac Med, Trabzon, Turkey

[4] Karadeniz Tech Univ, Dept Med Microbiol, Fac Med, Trabzon, Turkey

来源：

MEDITERRANEAN JOURNAL OF INFECTION MICROBES AND ANTIMICROBIALS | 2019年 / 8卷

关键词：

T-lymphocytopenia; idiopathic CD4-positive; rare diseases; Nocardia; nocardiosis; PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY; T-CELL LYMPHOCYTOPENIA; PATIENT; NOCARDIOSIS; MENINGITIS; RETINITIS; INFECTION; SECONDARY;

D O I：

10.4274/mjima.galenos.2019.2019.24

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Idiopathic CD4 lymphocytopenia (ICL), also known as non-HIV AIDS, is a rare disease characterized by opportunistic infections, malignancies, and autoimmune diseases. Idiopathic CD4 lymphocytopenia is defined as CD4+ T-lymphocyte level below 300/mm(3) in at least two measurements or less than 20% of total lymphocytes, which cannot be explained by any other condition, including HIV infection. Nocardia spp. are opportunistic microorganisms that is a frequent cause of infection in immunocompromised individuals. In this paper, we report a 50-year-old patient with ICL and intracranial brain abscess due to Nocardia farcinica and review th literature for related articles published between April 2012 and December 2018. These data suggest that there may be an underlying immunosuppression in adult patients who have infections that are recurrent, refractory, and caused by opportunistic pathogens.

引用

页数：8

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