Signaling dynamics of DNA damage response invoked by combination therapy are dose-dependent

被引:2
|
作者
Koh, Siang-Boon [1 ,2 ]
机构
[1] Harvard Med Sch, Boston, MA 02115 USA
[2] Massachusetts Gen Hosp, Canc Ctr, Boston, MA 02114 USA
关键词
GEMCITABINE;
D O I
10.1074/jbc.L119.007381
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:2191 / 2191
页数:1
相关论文
共 50 条
  • [31] RESERPINE REVERSAL RESPONSE BY IPRONIAZID - DOSE-DEPENDENT PHENOMENON
    HULL, LD
    HORITA, A
    NATURE, 1964, 202 (493) : 604 - &
  • [32] Dose-Dependent Response to Octreotide in Menetrier's Disease
    Sagvand, Babak Torabi
    Kamal, Afrin
    Lal, Pooja
    Vargo, John J.
    AMERICAN JOURNAL OF GASTROENTEROLOGY, 2018, 113 : S1462 - S1462
  • [33] Dose-dependent response of FGF-2 for lymphangiogenesis
    Chang, LK
    Garcia-Cardeña, G
    Farnebo, F
    Fannon, M
    Chen, EJ
    Butterfield, C
    Moses, MA
    Mulligan, RC
    Folkman, J
    Kaipainen, A
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2004, 101 (32) : 11658 - 11663
  • [34] Dose-Dependent Transcriptional Response to Ionizing Radiation Is Orchestrated with DNA Repair within the Nuclear Space
    Chaturvedi, Garima
    Sarusi-Portuguez, Avital
    Loza, Olga
    Shimoni-Sebag, Ariel
    Yoron, Orly
    Lawrence, Yaacov Richard
    Zach, Leor
    Hakim, Ofir
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2024, 25 (02)
  • [35] The dose-dependent response of vascular endothelium to blast injury
    Davies, E.
    Spear, A.
    Kirkman, E.
    Taylor, C.
    Midwinter, M.
    Watts, S.
    BRITISH JOURNAL OF SURGERY, 2013, 100 : 29 - 30
  • [36] Structural basis for phosphorylation-dependent signaling in the DNA-damage response
    Williams, RS
    Bernstein, N
    Lee, MS
    Rakovszky, ML
    Cui, D
    Green, R
    Weinfeld, M
    Glover, JNM
    BIOCHEMISTRY AND CELL BIOLOGY, 2005, 83 (06) : 721 - 727
  • [37] Dose-Dependent Hepatorenal Damage Induced by Erythrosine: A Study of Biochemical, Oxidative Stress, DNA Damage, and Histopathological Effects in Wistar Rats
    Singh, Mandeep
    Chadha, Pooja
    JOURNAL OF APPLIED TOXICOLOGY, 2025,
  • [38] Influence of Glucocorticoid-Therapy on the Disease Damage in Patients with Systemic Lupus Erythematosus is clearly dose-dependent
    Specker, C.
    NEPHROLOGE, 2016, 11 (01): : 3 - 3
  • [39] The DNA damage response: sensing and signaling
    McGowan, CH
    Russell, P
    CURRENT OPINION IN CELL BIOLOGY, 2004, 16 (06) : 629 - 633
  • [40] Bioflavonoids Cause Sustained DNA damage in a Drug- and Dose-Dependent Manner that Correlate with the Promotion of Chromosomal Translocations
    Goodenow, D. A.
    Richardson, C.
    ENVIRONMENTAL AND MOLECULAR MUTAGENESIS, 2018, 59 : 82 - 82