Eosinophils and eosinophil-associated diseases: An update

被引:84
|
作者
O'Sullivan, Jeremy A. [1 ]
Bochner, Bruce S. [1 ]
机构
[1] Northwestern Univ, Dept Med, Feinberg Sch Med, Div Allergy & Immunol, Chicago, IL 60611 USA
关键词
Eosinophilopoiesis; granule biogenesis; eosinophil subsets; apoptosis; adipose tissue; immunoregulation; asthma; chronic rhinosinusitis with nasal polyposis; biologicals; eosinophilic gastrointestinal disorder; SEVERE ATOPIC-DERMATITIS; CONTROLLED PHASE-3 TRIAL; DOUBLE-BLIND; CHRONIC RHINOSINUSITIS; PERSISTENT ASTHMA; BLOOD EOSINOPHILS; ADIPOSE-TISSUE; HYPEREOSINOPHILIC SYNDROMES; INHALED CORTICOSTEROIDS; GATA3-SPECIFIC DNAZYME;
D O I
10.1016/j.jaci.2017.09.022
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
The goal of this series is to offer a survey of the latest literature for clinicians and scientists alike, providing a list of important recent advances relevant to the broad field of allergy and immunology. This particular assignment was to cover the topic of eosinophils. In an attempt to highlight major ideas, themes, trends, and advances relevant to basic and clinical aspects of eosinophil biology, a search of articles published since 2015 in the Journal of Allergy and Clinical Immunology and other high-impact journals was performed. Articles were then reviewed and organized, and then key findings were summarized. Given space limitations, many outstanding articles could not be included, but the hope is that what follows provides a succinct overview of recently published work that has significantly added to our knowledge of eosinophils and eosinophil-associated diseases.
引用
收藏
页码:505 / 517
页数:13
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