Chromatin states and nuclear organization in development - a view from the nuclear lamina

被引:51
|
作者
Mattout, Anna [1 ]
Cabianca, Daphne S. [1 ]
Gasser, Susan M. [1 ,2 ]
机构
[1] Friedrich Miescher Inst Biomed Res, CH-4058 Basel, Switzerland
[2] Univ Basel, Fac Nat Sci, CH-4056 Basel, Switzerland
来源
GENOME BIOLOGY | 2015年 / 16卷
基金
瑞士国家科学基金会;
关键词
EMBRYONIC STEM-CELLS; TOPOLOGICALLY ASSOCIATING DOMAINS; DEACETYLASE; 3; HDAC3; B-TYPE LAMINS; A-TYPE LAMINS; CAENORHABDITIS-ELEGANS; GENOME-WIDE; BUDDING YEAST; MEMBRANE PROTEIN; MAMMALIAN-CELLS;
D O I
10.1186/s13059-015-0747-5
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
The spatial distribution of chromatin domains in interphase nuclei changes dramatically during development in multicellular organisms. A crucial question is whether nuclear organization is a cause or a result of differentiation. Genetic perturbation of lamina-heterochromatin interactions is helping to reveal the cross-talk between chromatin states and nuclear organization.
引用
收藏
页数:15
相关论文
共 50 条
  • [41] Chromatin organization and nuclear microenvironments in cancer cells
    He, Shihua
    Dunn, Katherine L.
    Espino, Paula S.
    Drobic, Bojan
    Li, Lin
    Yu, Jenny
    Sun, Jian-Min
    Chen, Hou Yu
    Pritchard, Susan
    Davie, James R.
    JOURNAL OF CELLULAR BIOCHEMISTRY, 2008, 104 (06) : 2004 - 2015
  • [42] Setting the boundaries of chromatin domains and nuclear organization
    Labrador, M
    Corces, VG
    CELL, 2002, 111 (02) : 151 - 154
  • [43] The nuclear matrix and the regulation of chromatin organization and function
    Davie, JR
    INTERNATIONAL REVIEW OF CYTOLOGY, VOL 162A: STRUCTURAL AND FUNCTIONAL ORGANIZATION OF THE NUCLEAR MATRIX, 1995, 162A : 191 - 250
  • [44] Nuclear lamina and nuclear matrix organization in sperm pronuclei assembled in Xenopus egg extract
    Zhang, CM
    Jenkins, H
    Goldberg, MW
    Allen, TD
    Hutchison, CJ
    JOURNAL OF CELL SCIENCE, 1996, 109 : 2275 - 2286
  • [45] ORGANIZATION OF MAMMALIAN CHROMATIN AND THE RADIOSENSITIVITY OF THE NUCLEAR PERIPHERY
    COLE, A
    BIOPHYSICAL JOURNAL, 1981, 33 (02) : A197 - A197
  • [46] Nuclear pore complexes in the functional organization of chromatin
    Nehrbass, U
    FASEB JOURNAL, 2001, 15 (05): : A865 - A865
  • [47] Cytoskeletal Control of Nuclear Morphology and Chromatin Organization
    Ramdas, Nisha M.
    Shivashankar, G. V.
    JOURNAL OF MOLECULAR BIOLOGY, 2015, 427 (03) : 695 - 706
  • [48] Structural Organization of the Nuclear Lamin Isoforms in the Nuclear Lamina Revealed by Super Resolution Microscopy
    Kittisopikul, M.
    Shimi, T.
    Tran, J.
    Goldman, A. E.
    Adam, S. A.
    Zheng, Y.
    Goldman, R. D.
    Jaqaman, K.
    MOLECULAR BIOLOGY OF THE CELL, 2015, 26
  • [49] Nuclear lamina component KAKU4 regulates chromatin states and transcriptional regulation in the Arabidopsis genome
    Cao, Yaxin
    Yan, Hengyu
    Sheng, Minghao
    Liu, Yue
    Yu, Xinyue
    Li, Zhongqiu
    Xu, Wenying
    Su, Zhen
    BMC BIOLOGY, 2024, 22 (01)
  • [50] High quality mapping of chromatin at or near the nuclear lamina from small numbers of cells reveals cell cycle and developmental changes of chromatin at the nuclear periphery
    Tran, Joseph R.
    Zheng, Xiaobin
    Adam, Stephen A.
    Goldman, Robert D.
    Zheng, Yixian
    NUCLEIC ACIDS RESEARCH, 2022, 50 (20) : E117