A rare brain tumor encountered: Phosphaturic mesenchymal tumor. Case report and review of the literature

被引:3
|
作者
Hadelsberg, Uri P. [1 ]
Doviner, Victoria [2 ,3 ]
Frankel, Meir [4 ]
Gonen, Lior [1 ]
Munter, Gabriel [4 ,5 ,6 ]
Margalit, Nevo [1 ]
机构
[1] Shaare Zedek Med Ctr, Dept Neurosurg, Shmuel Bait 12, IL-9103102 Jerusalem, Israel
[2] Shaare Zedek Med Ctr, Dept Pathol, Jerusalem, Israel
[3] Hebrew Univ Jerusalem, Hadassah Med Sch, Jerusalem, Israel
[4] Shaare Zedek Med Ctr, Internal Med Div, Endocrinol Diabet & Metab Unit, Jerusalem, Israel
[5] Shaare Zedek Med Ctr, Internal Med Dept, Jerusalem, Israel
[6] Shaare Zedek Med Ctr, Endocrinol Unit, Jerusalem, Israel
关键词
Tumor induced osteomalacia; Phosphaturic mesenchymal tumor; Oncogenic osteomalacia; INDUCED OSTEOMALACIA; TRANSPORT;
D O I
10.1016/j.inat.2018.12.010
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Rational: Phosphaturic mesenchymal tumors (PMTs) are rare tumors often causing tumor-induced osteomalacia (TIO), with surgical resection being the first line in the treatment of TIO. There are very few reports of PMTs located in the brain. The authors present one such case, it's management and outcome as well as a review of the literature. Patient concerns: The authors report of a 58 year old male with a background of osteoporosis, bone pain, muscle weakness and gait disturbances for the past several years. He presented to our institution with newly developed absence spells. He underwent imaging which revealed a brain tumor. Interventions: The patient underwent surgery for what was suspected as a meningioma. A gross total resection was done. The pathological diagnosis was that of phosphaturic mesenchymal tumor. Outcomes: Removal of the tumor helped in alleviating the patient's back symptoms immediately after surgery. The patient was discharged home and was followed up by an endocrinologist, with improvement of his bone pain, his muscle weakness and his gait disturbances. Lessons: PMT with involvement of the brain can be treated surgically. Removal of the tumor will alleviate symptoms in patients harboring this rare brain tumor.
引用
收藏
页码:91 / 94
页数:4
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