Application of modified antisense oligonucleotides and siRNAs as antiviral drugs

被引：14
|
作者：
Wagner, Anke [1 ]
Bock, Claus-Thomas [2 ]
Fechner, Henry [3 ]
Kurreck, Jens [3 ]
机构：
[1] Berlin Univ Technol, BioNukleo, Dept Bioproc Engn, Berlin, Germany
[2] Robert Koch Inst, Dept Infect Dis, Berlin, Germany
[3] Berlin Univ Technol, Inst Biotechnol, Dept Appl Biochem, Berlin, Germany
来源：
FUTURE MEDICINAL CHEMISTRY | 2015年 / 7卷 / 13期
关键词：
antisense oligonucleotide; antiviral therapy; delivery system; modified nucleotides; post-transcriptional gene silencing; siRNAs; EBOLA-VIRUS; RNA INTERFERENCE; DISCOVERY; INFECTION; PRIMATES;
D O I：
10.4155/fmc.15.114
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
引用
收藏
页码：1637 / 1642
页数：6
相关论文
共 50 条
  • [31] INHIBITION OF DENGUE VIRUS BY NOVEL, MODIFIED ANTISENSE OLIGONUCLEOTIDES
    RAVIPRAKASH, K
    LIU, K
    MATTEUCCI, M
    WAGNER, R
    RIFFENBURGH, R
    CARL, M
    JOURNAL OF VIROLOGY, 1995, 69 (01) : 69 - 74
  • [32] FLUORESCENCE-OPTICAL MEASUREMENTS OF CHLORIDE IN CELLS TREATED WITH ANTISENSE OLIGONUCLEOTIDES, ANTIVIRAL DRUGS FROM THE NUCLEOSIDE FAMILY OR PHENOL DERIVATIVES
    WOLL, E
    GSCHWENTNER, M
    BUEMBERGER, G
    PAULMICHL, M
    FASEB JOURNAL, 1995, 9 (03): : A302 - A302
  • [33] Antisense Inhibitors, Ribozymes, and siRNAs
    Thompson, Alexander J. V.
    Patel, Keyur
    CLINICS IN LIVER DISEASE, 2009, 13 (03) : 375 - +
  • [34] Immunostimulatory properties and antiviral activity of modified HBV-specific siRNAs
    Shin, Duckhyang
    Kim, Soo In
    Park, Mahnhoon
    Kim, Meehyein
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2007, 364 (03) : 436 - 442
  • [35] Antisense oligonucleotides
    Offensperger, WB
    Thoma, C
    Hasselblatt, P
    Blum, HE
    STATE OF THE ART HEPATOLOGY: MOLECULAR AND CELL BIOLOGY: IN HONOUR OF HANS POPPER'S 100TH BIRTHDAY, 2004, 138 : 202 - 209
  • [36] Antisense oligonucleotides
    Scoles, Daniel R.
    Minikel, Eric V.
    Pulst, Stefan M.
    NEUROLOGY-GENETICS, 2019, 5 (02)
  • [37] Antisense oligonucleotides
    Kashihara, N
    Maeshima, Y
    Makino, H
    EXPERIMENTAL NEPHROLOGY, 1998, 6 (01): : 84 - 88
  • [38] SUGAR MODIFIED OLIGONUCLEOTIDES FOR THE DESIGN OF POTENTIAL ANTIVIRAL AGENTS
    IMBACH, JL
    RAYNER, B
    ANTIVIRAL RESEARCH, 1988, 9 (1-2) : 155 - 155
  • [39] ANTISENSE OLIGONUCLEOTIDES
    DEMESMAEKER, A
    HANER, R
    MARTIN, P
    MOSER, HE
    ACCOUNTS OF CHEMICAL RESEARCH, 1995, 28 (09) : 366 - 374
  • [40] The pain of antisense: in vivo application of antisense oligonucleotides for functional genomics in pain and analgesia
    Stone, LS
    Vulchanova, L
    ADVANCED DRUG DELIVERY REVIEWS, 2003, 55 (08) : 1081 - 1112
12345