Fontolizumab (HuZAF™) pharmacokinetics (PK), pharmacodynamics (PD), immunogenicity and exposure/response relationship in patients (Pts) with moderate and severe Crohn's disease (CD)

被引:0
|
作者
Ding, H
Maia, M
Keller, S
Colombel, JF
van Deventer, S
Gendre, JP
Reinisch, W
Rutgeerts, P
Tang, MT
机构
关键词
D O I
暂无
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
引用
收藏
页码:A465 / A465
页数:1
相关论文
共 50 条
  • [41] Impact of immunogenicity on 2-year clinical outcomes in patients with moderate-to-severe Crohn's disease treated with subcutaneous infliximab: A post hoc analysis of the Phase 3 LIBERTY-CD study
    Sands, B. E.
    Colombel, J. F.
    Rubin, D. T.
    Schreiber, S.
    Siegel, C. A.
    Yarur, A.
    Danese, S.
    Kang, A.
    Kim, D. H.
    Lee, Y. N.
    Hanauer, S. B.
    JOURNAL OF CROHNS & COLITIS, 2025, 19 : I1254 - I1256
  • [42] Covariates Influencing the Exposure-Response Relationship for Certolizumab Pegol During the Induction and Maintenances Phases in Patients with Crohn's Disease
    Casteele, Niels Vande
    Feagan, Brian
    Vermeire, Severine
    Yassine, Mohamed
    Hasan, Iram
    Coarse, Jason
    Kosutic, Gordana
    Sandborn, William J.
    AMERICAN JOURNAL OF GASTROENTEROLOGY, 2016, 111 : S262 - S263
  • [43] Relationship Between Protocol Specified Corticosteroid Tapering Regimens and Achieving Outcome Measures in Patients With Moderate-Severe Ulcerative Colitis and Crohn's Disease
    George, John
    Singh, Siddharth
    Dulai, Parambir
    Ma, Christopher
    Tran Nguyen
    Feagan, Brian G.
    Sandborn, William J.
    Jairath, Vipul
    AMERICAN JOURNAL OF GASTROENTEROLOGY, 2019, 114 : S448 - S448
  • [44] Correlation between trough levels of risankizumab and clinical and biological remission in patients with moderate to severe Crohn's disease: a retrospective multicenter study (RISE-CD)
    Sequier, L.
    Altwegg, R.
    Barrau, M.
    Bozon, A.
    Nancey, S.
    Boschetti, G.
    Roblin, X.
    Caillo, L.
    JOURNAL OF CROHNS & COLITIS, 2025, 19 : i1730 - i1730
  • [45] Rapid induction of remission and clinical response with adalimumab in patients with moderate to severe Crohn's disease and secondary failure to infliximab therapy: Results of the gain studya
    Columbel, J.
    Rutgeerts, P.
    Sandborn, W. J.
    Enns, R.
    Hanauer, S. B.
    Kent, J. D.
    Pollack, P. F.
    GUT, 2007, 56 : A109 - A109
  • [46] RAPID SYMPTOMATIC IMPROVEMENT WITH SUBCUTANEOUS INFLIXIMAB INDUCTION TREATMENT FOR PATIENTS WITH MODERATE TO SEVERE CROHN'S DISEASE: FIRST RESULTS FROM THE DIRECT-CD STUDY
    Anjie, Suzanne I.
    Jharap, Bindia
    Jansen, Jeroen M.
    Mares, Wout
    Duijvestein, Marjolijn
    Maljaars, Jeroen
    Oldenburg, Bas
    D'Haens, Geert
    Gecse, Krisztina
    GASTROENTEROLOGY, 2024, 166 (05) : S510 - S510
  • [47] Comparative Efficacy of Pharmacological Agents for Moderate-Severe Crohn's Disease in Patients with Prior Exposure to Anti-TNF Agents: A Network Meta-Analysis
    Singh, Siddharth
    Fumery, Mathurin
    Dulai, Parambir
    Murad, Mohammad
    Sandborn, William
    INFLAMMATORY BOWEL DISEASES, 2017, 23 : S44 - S44
  • [48] Safety and tolerability of antagonist anti-human CD40 Mab ch5D12 in patients with moderate to severe Crohn's disease
    Kasran, A
    Boon, L
    Wortel, CH
    Van Hogezand, RA
    Schreiber, S
    Goldin, E
    De Boer, M
    Geboes, K
    Rutgeerts, P
    Ceuppens, JL
    ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 2005, 22 (02) : 111 - 122
  • [49] Rapid symptomatic improvement with subcutaneous infliximab induction treatment for patients with moderate-to-severe Crohn's disease: first results from the DIRECT-CD study
    Anjie, S.
    Jharap, B.
    Jansen, J. M.
    Mares, W. G.
    Duijvestein, M.
    Maljaars, J. P. W.
    Oldenburg, B.
    D'Haens, G. R. A. M.
    Gecse, K. B.
    JOURNAL OF CROHNS & COLITIS, 2024, 18 : I1682 - I1683
  • [50] Efficacy and Safety of Dose Adjustment and Delayed Response to Ustekinumab in Moderate - Severe Crohn's Disease Patients: Results from the IM-UNITI Maintenance Study
    Sands, Bruce
    Gasink, Chris
    Jacobstein, Doug
    Gao, Long Long
    Johanns, Jewel
    Szapary, Philippe
    Colombel, Jean-Frederic
    Targan, Stephan
    Ghosh, Subrata
    Sandborn, William J.
    AMERICAN JOURNAL OF GASTROENTEROLOGY, 2016, 111 : S302 - S303