Surface layers of 6-thioguanine on the mercury electrode

被引:9
|
作者
Arias, ZG [1 ]
Alvarez, JLM [1 ]
Fonseca, JML [1 ]
机构
[1] Univ Oviedo, Dept Quim Fis & Analit, E-33071 Oviedo, Asturias, Spain
关键词
6-thioguanine; chemical and physical adsorption; condensed monolayers; ac voltammetry; cyclic voltammetry;
D O I
10.1006/jcis.2002.8339
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
The adsorption behavior of 6-thioguanine (6TG) on a hanging mercury drop electrode has been studied with ac and cyclic voltammetry in 0.1 M Na2SO4 and 0.01 M sodium acetate solutions at pH 4.3. Several condensed phases of chemically adsorbed 6TG as well as one phase of physically adsorbed 6TG have been characterized. Under total coverage conditions, the films of chemiadsorbed molecules inhibit rather efficiently the electrode reaction of mercury oxide formation. (C) 2002 Elsevier Science (USA).
引用
收藏
页码:295 / 302
页数:8
相关论文
共 50 条
  • [31] 6-Thioguanine Biosynthesis in Erwinia Species
    Wensing, A.
    Gernold, M.
    Jock, S.
    Jelkmann, W.
    Geider, K.
    Beck, A.
    Jansen, R.
    XIII INTERNATIONAL WORKSHOP ON FIRE BLIGHT, 2014, 1056 : 165 - 167
  • [32] 6-Thioguanine in children with acute lymphoblastic leukaemia: influence of food on parent drug pharmacokinetics and 6-thioguanine nucleotide concentrations
    Lancaster, DL
    Patel, N
    Lennard, L
    Lilleyman, JS
    BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 2001, 51 (06) : 531 - 539
  • [33] The determination of nonelectroactive anticancer drug 6-thioguanine on DNA-modified gold electrode
    Wang, SF
    Xie, F
    Hu, RF
    Cai, HC
    ANALYTICAL LETTERS, 2006, 39 (06) : 1041 - 1052
  • [34] Electrochemical monitoring of surface confined interaction between 6-Thioguanine and DNA by using single-use graphite electrode
    Eksin, Ece
    Congur, Gulsah
    Mese, Fehmi
    Erdem, Arzum
    JOURNAL OF ELECTROANALYTICAL CHEMISTRY, 2014, 733 : 33 - 38
  • [35] MECHANISM OF ACTION OF 6-THIOGUANINE (6-TG)
    NELSON, JA
    KUHNS, J
    PHARMACOLOGIST, 1974, 16 (02): : 209 - 209
  • [36] Effect of 6-thioguanine on the stability of duplex DNA
    Bohon, J
    de los Santos, CR
    NUCLEIC ACIDS RESEARCH, 2005, 33 (09) : 2880 - 2886
  • [37] 6-METHYLTHIOGUANYLIC ACID, A METABOLITE OF 6-THIOGUANINE
    ALLAN, PW
    BENNETT, LL
    BIOCHEMICAL PHARMACOLOGY, 1971, 20 (04) : 847 - +
  • [38] Determination of 6-thioguanine based on localized surface plasmon resonance of gold nanoparticle
    Bi, Ning
    Hu, Meihua
    Zhu, Hongyu
    Qi, Haibo
    Tian, Yuan
    Zhang, Hanqi
    SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2013, 107 : 24 - 30
  • [39] RADIOSENSITIZATION OF 2 MURINE FIBROSARCOMAS WITH 6-THIOGUANINE
    KIM, JH
    ALFIERI, AA
    KIM, SH
    HONG, SS
    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1990, 18 (03): : 583 - 586
  • [40] ASSAY OF 6-THIOGUANINE NUCLEOTIDE, A MAJOR METABOLITE OF AZATHIOPRINE, 6-MERCAPTOPURINE AND 6-THIOGUANINE, IN HUMAN RED-BLOOD-CELLS
    LENNARD, L
    MADDOCKS, JL
    JOURNAL OF PHARMACY AND PHARMACOLOGY, 1983, 35 (01) : 15 - 18