Expression of a homeobox gene Msx-1 involved in craniofacial abnormalities in transgenic mice

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作者：
Takahashi, T
Guron, C
Raghow, R
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XXX WORLD CONGRESS OF THE INTERNATIONAL COLLEGE OF SURGEONS, VOLS 1-2 | 1996年
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R61 [外科手术学];
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摘要：
To decipher the developmental basis of expression of Msx-1 gene, we introduced DNA constructs in which luciferase or beta-galactosidase (lacZ) reporter genes were driven by the potential cis-regulatory sequences of Msx-1 into NIH 3T3 and C2C12 cells, and in transgenic mice. Analysis of expression of the reporter genes revealed a glimpse into the complexity of the regulatory elements of Msx-1 promoter which activate it in vitro in cultured cells and during embryogenesis.
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页码：1675 / 1679
页数：5
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