Direct electron transfer of cytochrome c at mono-dispersed and negatively charged perylene-graphene matrix

被引:21
|
作者
Zhang, Nan [1 ]
Lv, Xiangyu [1 ]
Ma, Weiguang [1 ]
Hu, Yuwei [1 ]
Li, Fenghua [1 ]
Han, Dongxue [1 ]
Niu, Li [1 ,2 ]
机构
[1] Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Electroananlyt Chem, Engn Lab Modern Analyt Tech, Changchun 130022, Peoples R China
[2] Changzhou Inst Energy Storage Mat & Devices, Changzhou 213001, Peoples R China
关键词
Cytochrome c; Direct electron transfer; 3,4,9,10-perylene tetracarboxylic acid; Graphene; NANOTUBES-MODIFIED ELECTRODE; EXFOLIATED GRAPHITE OXIDE; SELF-ASSEMBLED MONOLAYERS; DIRECT ELECTROCHEMISTRY; CARBON NANOTUBES; COMPOSITE FILM; ELECTROCATALYTIC ACTIVITY; FUNCTIONALIZED GRAPHENE; AQUEOUS DISPERSIONS; TRANSFER KINETICS;
D O I
10.1016/j.talanta.2012.12.028
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Mono-dispersed 3,4,9,10-perylene tetracarboxylic acid (PICA) functionalized graphene sheets (PTCA-graphene) were fabricated by a chemical route and dispersed well in aqueous solution. PTCA-graphene with plenty of -COOH groups as electrostatic absorbing sites were beneficial to the loading of Cytochrome c (Cyt c). Cyt c, which was tightly immobilized on the PTCA-graphene modified glassy carbon electrode, maintained its natural conformation. Direct electron transfer of Cyt c and the electro-catalytic activity towards the reduction of H2O2 were also achieved. It has been substantiated that PTCA-graphene is a preferable biocompatible matrix for Cyt c. (C) 2012 Elsevier B.V. All rights reserved.
引用
收藏
页码:195 / 202
页数:8
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