Clinical experience with the use of cyclosporin A in psoriasis.: Results of a retrospective study

被引：10

作者：

Ojeda, R ^{[1
]}

Regaña, MS ^{[1
]}

Massana, J ^{[1
]}

Oliete, R ^{[1
]}

Umbert, P ^{[1
]}

机构：

[1] Hosp Sagrat Cor, Dept Dermatol, Psoriasis Unit, Barcelona 08029, Spain

来源：

JOURNAL OF DERMATOLOGICAL TREATMENT | 2005年 / 16卷 / 04期

关键词：

cyclosporin A; psoriasis; continuous therapy;

D O I：

10.1080/09546630510011829

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

The efficacy of cyclosporin A (Sandimmun NeoralH) in severe psoriasis was analysed in 70 patients included in a retrospective descriptive study conducted at our Dermatology Department from January 1994 until December 2000. After 8 weeks of treatment, with an initial dose of 2.5-3 mg/kg/day, the reduction in the Psoriasis Area and Severity Index (PASI) score was > 5% in 61% of patients. Most of the side effects observed turned out to be susceptible to being reversed over time or by dose reduction. The results of this study show that continuous and low-dose cyclosporin therapy is a safe and efficacious treatment for severe chronic psoriasis.

引用

页码：238 / 241

页数：4

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