Identification of Toll-like receptor 4 (Tlr4) as the sole conduit for LPS signal transduction: genetic and evolutionary studies

被引：93
|
作者：
Beutler, B [1 ]
Du, X [1 ]
Poltorak, A [1 ]
机构：
[1] Scripps Res Inst, Dept Immunol IMM 31, La Jolla, CA 92037 USA
来源：
JOURNAL OF ENDOTOXIN RESEARCH | 2001年 / 7卷 / 04期
关键词：
D O I：
10.1179/096805101101532846
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
[No abstract available]
引用
收藏
页码：277 / 280
页数：4
相关论文
共 50 条
  • [21] A closer look at Toll-like receptor 4 (TLR4) and toll-like receptor 20 (TLR20) of common carp (Cyprinus carpio)
    Pietretti, D.
    Forlenza, M.
    Fink, I. R.
    Wiegerijes, G.
    FISH & SHELLFISH IMMUNOLOGY, 2013, 34 (06) : 1673 - 1673
  • [22] Amphiphilic Guanidinocalixarenes Inhibit Lipopolysaccharide (LPS)- and Lectin-Stimulated Toll-like Receptor 4 (TLR4) Signaling
    Sestito, Stefania E.
    Facchini, Fabio A.
    Morbioli, Ilaria
    Billod, Jean-Marc
    Martin-Santamaria, Sonsoles
    Casnati, Alessandro
    Sansone, Francesco
    Peri, Francesco
    JOURNAL OF MEDICINAL CHEMISTRY, 2017, 60 (12) : 4882 - 4892
  • [23] Injury augments Toll-like receptor responses independently of TLR4
    Lederer, JA
    Purcell, EM
    Shelley, OP
    Mannick, JA
    Paterson, HM
    JOURNAL OF LEUKOCYTE BIOLOGY, 2001, : 33 - 33
  • [24] Toll-like Receptor 4 (TLR4) Modulation by Synthetic and Natural Compounds: An Update
    Peri, Francesco
    Calabrese, Valentina
    JOURNAL OF MEDICINAL CHEMISTRY, 2014, 57 (09) : 3612 - 3622
  • [25] Toll-like receptor 4 (TLR4) polymorphisms in Iranian patients with visceral leishmaniasis
    Manoochehr Rasouli
    Maryam Keshavarz
    Mehdi Kalani
    Ali Moravej
    Simin Kiany
    Parisa Badiee
    Molecular Biology Reports, 2012, 39 : 10795 - 10802
  • [26] Polymorphisms in Toll-like receptor 4 (TLR4) are associated with protection against leprosy
    P.-Y. Bochud
    D. Sinsimer
    A. Aderem
    M. R. Siddiqui
    P. Saunderson
    S. Britton
    I. Abraham
    A. Tadesse Argaw
    M. Janer
    T. R. Hawn
    G. Kaplan
    European Journal of Clinical Microbiology & Infectious Diseases, 2009, 28
  • [27] The role of Toll-like receptor 4 (TLR4) in the COPD and the human influence on moxifloxacin
    Knobloch, J.
    Jungck, D.
    Chikosi, S.
    Schild, K.
    Koch, A.
    INFECTION, 2009, 37 : 27 - 28
  • [28] Toll-like receptor 4 (TLR4) polymorphisms in Iranian patients with visceral leishmaniasis
    Rasouli, Manoochehr
    Keshavarz, Maryam
    Kalani, Mehdi
    Moravej, Ali
    Kiany, Simin
    Badiee, Parisa
    MOLECULAR BIOLOGY REPORTS, 2012, 39 (12) : 10795 - 10802
  • [29] Toll-like receptor 4 (TLR4) mediates cavernosal dysfunction in diabetic rats
    Nunes, Kenia Pedrosa
    Carrilo-Sepulveda, Maria Alicia
    Szasz, Theodora
    Webb, R. Clinton
    FASEB JOURNAL, 2013, 27
  • [30] Therapeutic targeting of innate immunity with Toll-like receptor 4 (TLR4) antagonists
    Peri, Francesco
    Piazza, Matteo
    BIOTECHNOLOGY ADVANCES, 2012, 30 (01) : 251 - 260
12345