Analgesic Effect of Xenon in Rat Model of Inflammatory Pain

被引：2
|
作者：
Kukushkin, M. L. [1 ,2 ]
Igon'kina, S. I. [1 ]
Potapov, S. V. [1 ]
Potapov, A. V. [1 ]
机构：
[1] Res Inst Gen Pathol & Pathol Physiol, Moscow, Russia
[2] IM Sechenov First Moscow State Med Univ, Moscow, Russia
来源：
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2017年 / 162卷 / 04期
关键词：
xenon; analgesia; rat; formalin inflammatory pain model;
D O I：
10.1007/s10517-017-3637-x
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
The analgesic effects of inert gas xenon were examined on rats. The formalin model of inflammatory pain, tail-flick test, and hot-plate test revealed the antinociceptive effects of subanesthetizing doses of inhalation anesthetic xenon. Inhalation of 50/50 xenon/oxygen mixture moderated the nociceptive responses during acute and tonic phases of inflammatory pain.
引用
收藏
页码：451 / 453
页数：3
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