Gene therapy for recessive dystrophic epidermolysis bullosa using COL7A1 gene corrected autologous fibroblasts

被引:0
|
作者
Abdul-Wahab, A. [1 ,2 ]
Georgiadis, C. [1 ]
Qasim, W. [1 ]
Thrasher, A. [1 ]
McGrath, J. A. [2 ]
Di, W. [1 ]
机构
[1] Inst Child Hlth, London, England
[2] Kings Coll London, London WC2R 2LS, England
关键词
D O I
暂无
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
843
引用
收藏
页码:S143 / S143
页数:1
相关论文
共 50 条
  • [21] Comparing COL7A1 Gene Expression in Fibroblast Cells of Dystrophic Epidermolysis Bullosa Patients with Clinical Responses to Autologous Fibroblasts Transplantation
    Eslami, Maryam
    Golshanfard, Majid
    Bajouri, Amir
    Aghdami, Nasser
    Mohammadi, Mahsa
    Shafieian, Saeed
    Memarsadeghi, Omeed
    Seifalian, Alexander
    JOURNAL OF CONTEMPORARY MEDICAL SCIENCES, 2023, 9 (01): : 18 - 23
  • [22] The novel mutation in the COL7A1 gene in the patient with dystrophic forms of epidermolysis bullosa
    Taghdiri, Maryam
    Naeimi, Sirous
    Fardaei, Majid
    Tabei, Seyed Mohammad Bagher
    GENE REPORTS, 2020, 21
  • [23] A Novel Heterozygous Missense Mutation in COL7A1 Gene in Dystrophic Epidermolysis Bullosa
    Kakar, Kalsoom
    Ajmal, Nida
    Khan, Sanam Zeib
    Shehzad, Paras
    Malik, Maryam
    Sadia, Haleema
    Wali, Abdul
    Shaikh, Rozeena
    INTERNATIONAL JOURNAL OF HUMAN GENETICS, 2021, 21 (03) : 102 - 109
  • [24] Fibroblasts show more potential as target cells than keratinocytes in COL7A1 gene therapy of dystrophic epidermolysis bullosa
    Goto, Maki
    Sawamura, Daisuke
    Ito, Kei
    Abe, Masataka
    Nishie, Wataru
    Sakai, Kaori
    Shibaki, Akihiko
    Akiyama, Masashi
    Shimizu, Hiroshi
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2006, 126 (04) : 766 - 772
  • [25] Exon 87 skipping of the COL7A1 gene in dominant dystrophic epidermolysis bullosa
    Koga, Hiroshi
    Hamada, Takahiro
    Ishii, Norito
    Fukuda, Shunpei
    Sakaguchi, Sachiko
    Nakano, Hajime
    Tamai, Katuto
    Sawamura, Daisuke
    Hashimoto, Takashi
    JOURNAL OF DERMATOLOGY, 2011, 38 (05): : 489 - 492
  • [26] Exon 87 skipping of the COL7A1 gene in dominant dystrophic epidermolysis bullosa
    Koga, Hiroshi
    Hamada, Takahiro
    Ishii, Norito
    Fukuda, Shunpei
    Sakaguchi, Sachiko
    Nakano, Hajime
    Tamai, Katsuto
    Sawamura, Daisuke
    Hashimoto, Takashi
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2010, 130 : S81 - S81
  • [27] A Phase-I Safety Study Protocol for Lentiviral-Mediated COL7A1 Gene-Modified Autologous Fibroblasts in Recessive Dystrophic Epidermolysis Bullosa
    Syed, Farhatullah
    Di, Wei-Li
    Petrova, Anastasia
    Abdul-Wahab, Alya
    Georgiadis, Christos
    Lwin, Su M.
    Thrasher, Adrian
    McGrath, John
    Qasim, Waseem
    MOLECULAR THERAPY, 2015, 23 : S265 - S265
  • [28] Glycine substitution mutations in the COL7A1 gene underlying both dominant and recessive forms of dystrophic epidermolysis bullosa
    Almaani, N.
    Liu, L.
    Dopping-Hepenstal, P. D. C.
    Wong, A.
    Moss, C.
    Nanda, A.
    McGrath, J. A.
    BRITISH JOURNAL OF DERMATOLOGY, 2008, 158 (04) : 907 - 907
  • [29] Development of Minicircle Vectors Encoding COL7A1 Gene with Human Promoters for Non-Viral Gene Therapy for Recessive Dystrophic Epidermolysis Bullosa
    Wang, Xianqing
    Alshehri, Fatma
    Manzanares, Dario
    Li, Yinghao
    He, Zhonglei
    Qiu, Bei
    Zeng, Ming
    Sigen, A.
    Lara-Saez, Irene
    Wang, Wenxin
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 22 (23)
  • [30] Recessive epidermolysis bullosa due to composite heterozygote mutations in the COL7A1 gene
    Abdou, A.
    Daoui, L.
    Charlesworth, A.
    Chiaverini, C.
    Algros, M-P
    Puzenat, E.
    Chantegret, C.
    Vabres, P.
    Lacour, J-P
    Aubin, F.
    ANNALES DE DERMATOLOGIE ET DE VENEREOLOGIE, 2015, 142 (05): : 346 - 349