MULTI-SPECTRAL TUNABLE EXCITATION FLUORESCENCE MICROSCOPY WITH A NANOIMPRINTED PDMS-ON-SILICON GRATING OPTICAL FILTER

被引:0
|
作者
Huang, N. -T. [1 ]
Truxal, S. [1 ]
Tung, Y. -C. [1 ]
Kurabayashi, K. [1 ]
机构
[1] Univ Michigan, Ann Arbor, MI 48109 USA
关键词
SINGLE MOLECULES;
D O I
暂无
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
We report a MEMS-based tunable grating optical filter device and its integration with a fluorescence microscope system. This integration allows for voltage-controlled wavelength tuning of excitation light from a multi-band source. We demonstrate the system's capability to selectively excite fluorescence protein molecules with different excitation/emission spectral characteristics using a chip of optical filter device arrays, each with a very small (2mm x 2 mm) footprint. The demonstrated technology has potential to enable massively-parallel multispectral fluorescence microscopy in biochip array settings.
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页数:4
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