Chiral resolution of the dansyl derivative of 2-methyltaurine by capillary electrophoresis

被引：11
|
作者：
Anselmi, S
Braghiroli, D
DiBella, M
Schmid, MG
Wintersteiger, R
Gubitz, G
机构：
[1] UNIV MODENA,DIPARTIMENTO SCI FARMACEUT,I-41100 MODENA,ITALY
[2] KARL FRANZENS UNIV GRAZ,INST PHARMAZEUT CHEM,A-8010 GRAZ,AUSTRIA
来源：
JOURNAL OF CHROMATOGRAPHY B-BIOMEDICAL APPLICATIONS | 1996年 / 681卷 / 01期
关键词：
enantiomer separation; 2-methyltaurine; taurine;
D O I：
10.1016/0378-4347(95)00532-3
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
A cyclodextrin-modified micellar capillary electrophoretic method was developed for the chiral separation of 2-methyltaurine. The racemic mixture was separated after derivatization with dansyl chloride. The enantiomeric separation of the dansyl derivative was done using electrolyte solutions containing beta-cyclodextrin (beta-CD) or different ratios of beta- and gamma-CD. The mixture of beta- and gamma-CD optimally resolved the compound studied.
引用
收藏
页码：83 / 86
页数：4
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