Expression of ErbB proteins in human prostate

被引：5
|
作者：
Nasu, K
Tanji, N [1 ]
Nishioka, R
Wang, J
Yanagihara, Y
Ozawa, A
Yokoyama, M
机构：
[1] Ehime Univ, Sch Med, Dept Urol, Tohon City, Ehime 7910295, Japan
[2] Ehime Univ, Sch Med, Dept Orthopaed Surg, Tohon City, Ehime 7910295, Japan
来源：
ARCHIVES OF ANDROLOGY | 2006年 / 52卷 / 03期
关键词：
ErbBs; immunohistochemistry; prostate;
D O I：
10.1080/01485010500316238
中图分类号：
R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
摘要：
ErbB proteins are widely expressed in human and animal tissues, notably in cells of epithelial or neuroendocrine origin. Protein expression and interactions of ErbBs were examined in prostate cancer specimens. Expression of ErbB1-4 proteins was determined with immunohistochemical methods using each monoclonal antibody in 20 prostatic adenocarcinomas. The 4 ErbB proteins were widely expressed in normal, hyperplastic and cancerous tissues of the prostate. ErbBs may contribute to normal development or tumor growth and progression in human prostate.
引用
收藏
页码：185 / 190
页数：6
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