Donor Body Mass Index as a Risk Factor for Delayed Onset of Graft Function

被引:2
|
作者
Miklusica, Juraj [1 ,2 ]
Dedinska, Ivana [1 ,2 ]
Palkoci, Blazej [1 ,2 ]
Sendrey, Alexander [2 ,3 ]
Lajciakova, Mariana [2 ,4 ]
Vojtko, Martin [1 ,2 ]
Osinova, Denisa
Laca, L'udovit [1 ,2 ]
机构
[1] Univ Hosp Martin, Surg Clin & Transplant Ctr, Kollarova 2, Martin 03601, Slovakia
[2] Comenius Univ, Jessenius Fac Med, Martin, Slovakia
[3] Univ Hosp Martin, Dept Common Operating Rooms, Martin, Slovakia
[4] Univ Hosp Martin, Dept Anaesthesiol & Intens Med, Martin, Slovakia
关键词
body mass index; donor after brain death; kidney transplantation; delayed graft function; graft function; KIDNEY-TRANSPLANTATION; RENAL-TRANSPLANTATION; CARDIAC DEATH; DONATION;
D O I
10.1177/1526924817746911
中图分类号
R61 [外科手术学];
学科分类号
摘要
Delayed graft function continues to pose a significant challenge to clinicians in the context of kidney transplantation. The objective of this retrospective, 5-year analysis is to identify the parameters of beating heart donors and those of recipients that affect the delayed development of graft function. The monitored group was composed of 152 beating heart donors and 179 recipients. Delayed graft function was identified in 32 (17%) patients. The predictor for development of delayed graft function was the body mass index of the donor (odds ratio: 1.1473; 95% confidence interval [CI]: 1.0017-1.3140; P = .0472), and the independent risk factors were donor body mass index 30 to 34.9 kg/m(2) (hazard ratio [HR]: 6.0215; 95% CI: 1.4188-25.556; P = .0149), donor body mass index >= 35 kg/m(2) (HR: 13.5484; 95% CI: 1.4575-125.938; P = .0220), and abuse of alcohol in the donor's history (HR: 1.779; 95% CI: 1.0679-2.964; P = .0270).
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页码:87 / 90
页数:4
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