Notch ligand Delta-like 4 regulates development and pathogenesis of allergic airway responses by modulating IL-2 production and Th2 immunity

被引:0
|
作者
Jang, Sihyug [1 ]
Schaller, Matthew [1 ]
Lukacs, Nicholas [1 ]
机构
[1] Univ Michigan, Pathol, Ann Arbor, MI 48109 USA
来源
JOURNAL OF IMMUNOLOGY | 2010年 / 184卷
关键词
D O I
暂无
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
141.15
引用
收藏
页数:2
相关论文
共 50 条
  • [31] Dendritic cell expression of interferon regulatory factor 4 drives Th2 responses and regulates IL-10 and IL-33 production
    Williams, Jesse
    Tjota, Melissa
    Clay, Bryan
    Fixsen, Bethany
    Singh, Harinder
    Sciammas, Roger
    Sperling, Anne
    JOURNAL OF IMMUNOLOGY, 2013, 190
  • [32] CD4+ Th2 cells are directly regulated by IL-10 during allergic airway inflammation
    Coomes, S. M.
    Kannan, Y.
    Pelly, V. S.
    Entwistle, L. J.
    Guidi, R.
    Perez-Lloret, J.
    Nikolov, N.
    Mueller, W.
    Wilson, M. S.
    MUCOSAL IMMUNOLOGY, 2017, 10 (01) : 150 - 161
  • [33] IL-25 Promotes Th2 Immunity Responses in Airway Inflammation of Asthmatic Mice via Activation of Dendritic Cells
    Li Hongjia
    Zhang Caiqing
    Lu Degan
    Liu Fen
    Wang Chao
    Wu Jinxiang
    Dong Liang
    INFLAMMATION, 2014, 37 (04) : 1070 - 1077
  • [34] IL-25 Promotes Th2 Immunity Responses in Airway Inflammation of Asthmatic Mice via Activation of Dendritic Cells
    Li Hongjia
    Zhang Caiqing
    Lu Degan
    Liu Fen
    Wang Chao
    Wu Jinxiang
    Dong Liang
    Inflammation, 2014, 37 : 1070 - 1077
  • [35] Eosinophils function as IL-4-controlled cellular amplifiers for Th2 cytokine production in the late-phase response of allergic airway inflammation
    Chen, LQ
    Xin, JP
    Coleman, J
    Huang, Z
    Huang, H
    FASEB JOURNAL, 2003, 17 (07): : C250 - C250
  • [36] Tim-4 is the ligand for Tim-1, and the Tim-1/Tim-4 interaction regulates the development of Th2 responses
    Meyers, JH
    Chakravarti, S
    Schlesinger, D
    Illes, Z
    Waldner, H
    Umetsu, SE
    Kenny, J
    Zheng, XX
    Umetsu, DT
    DeKruyff, RH
    Strom, TB
    Kuchroo, VK
    FASEB JOURNAL, 2005, 19 (04): : A905 - A905
  • [37] The iron sequestering protein Lipocalin 2 is critical to IL-33-exposed dendritic cell stimulation of Th2 responses and allergic airway disease
    Lott, Jeremy
    Liu, Quan
    Matta, Benjamin
    Mathews, Lisa
    Pociask, Derek
    Sperling, Anne
    Kolls, Jay
    Turnquist, Heth
    JOURNAL OF IMMUNOLOGY, 2015, 194
  • [38] A Fully Human IL4Rα Antibody for Inhibition of IL-4/IL-13-driven Th2 Responses in Allergic Disease
    Kostic, Ana
    Zhang, Wen
    Dore, Anthony
    Coopey, Blerta
    MacDonald, Douglas
    Fury, Wen
    Lin, Calvin
    Hamilton, Jennifer
    Classon, Brendan
    Papadopoulos, Nicholas J.
    Murphy, Andrew
    CLINICAL IMMUNOLOGY, 2010, 135 : S105 - S106
  • [39] A 3′ enhancer in the IL-4 gene regulates cytokine production by Th2 cells and mast cells
    Solymar, DC
    Agarwal, S
    Bassing, CH
    Alt, FW
    Rao, A
    IMMUNITY, 2002, 17 (01) : 41 - 50
  • [40] Stat6 is required for mediating responses to IL-4 and for the development of Th2 cells
    Kaplan, MH
    Schindler, U
    Smiley, ST
    Grusby, MJ
    IMMUNITY, 1996, 4 (03) : 313 - 319