Pregnane X Receptor Mediates Dyslipidemia Induced by the HIV Protease Inhibitor Amprenavir in Mice

被引：0
|
作者：
Helsley, Robert Nathaniel [1 ]
Sui, Yipeng [1 ]
Ai, Ni [2 ]
Park, Se-Hyung [1 ]
Welsh, William J. [2 ]
Zhou, Changcheng [1 ]
机构：
[1] Univ Kentucky, Grad Ctr Nutr Sci, Lexington, KY USA
[2] Univ Med & Dent New Jersey, Dept Pharmacol, Piscataway, NJ 08854 USA
来源：
FASEB JOURNAL | 2013年 / 27卷
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
1169.20
引用
收藏
页数：1
相关论文
共 50 条
  • [31] PREGNANE X RECEPTOR DEFICIENCY PROTECTS FEMALE MICE AGAINST CHRONIC ETHANOL-INDUCED HEPATOTOXICITY
    Choi, S.
    Neequaye, P.
    Gonzalez, F. J.
    Gyamfi, M. A.
    ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH, 2018, 42 : 82A - 82A
  • [32] Protocatechuic acid inhibits LPS-induced mastitis in mice through activating the pregnane X receptor
    Zhao, Lihua
    Jin, Lei
    Yang, Bin
    JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2023, 27 (16) : 2321 - 2327
  • [33] Pregnane X receptor (PXR) protects against cisplatin-induced acute kidney injury in mice
    Luan, Zhilin
    Wei, Yuanyi
    Huo, Xiaoxiao
    Sun, Xiaowan
    Zhang, Cong
    Ming, Wenhua
    Luo, Zhaokang
    Du, Chunxiu
    Li, Yaqing
    Xu, Hu
    Lu, Heyuan
    Zheng, Feng
    Guan, Youfei
    Zhang, Xiaoyan
    BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 2021, 1867 (03):
  • [34] Role of P-glycoprotein on the CNS disposition of amprenavir (141W94), an HIV protease inhibitor
    Polli, JW
    Jarrett, JL
    Studenberg, SD
    Humphreys, JE
    Dennis, SW
    Brouwer, KR
    Woolley, JL
    PHARMACEUTICAL RESEARCH, 1999, 16 (08) : 1206 - 1212
  • [35] IGFBP1 mediates pregnane X receptor-induced morphological changes and migration of hepatocellular carcinoma cells
    Yamazaki, Y.
    Kodama, S.
    Kakizaki, S.
    Yamada, M.
    Negishi, M.
    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2015, 30 : 329 - 329
  • [36] Pregnane X receptor and drug-induced liver injury
    Wang, Yue-Ming
    Chai, Sergio C.
    Brewer, Christopher T.
    Chen, Taosheng
    EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY, 2014, 10 (11) : 1521 - 1532
  • [37] In Vivo Responses of the Human and Murine Pregnane X Receptor to Dexamethasone in Mice
    Scheer, Nico
    Ross, Jillian
    Kapelyukh, Yury
    Rode, Anja
    Wolf, C. Roland
    DRUG METABOLISM AND DISPOSITION, 2010, 38 (07) : 1046 - 1053
  • [38] CYP3A4 and pregnane X receptor humanized mice
    Gonzalez, Frank J.
    JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY, 2007, 21 (04) : 158 - 162
  • [39] Role of Pregnane X Receptor in Obesity and Glucose Homeostasis in Male Mice
    Spruiell, Krisstonia
    Richardson, Ricardo M.
    Cullen, John M.
    Awumey, Emmanuel M.
    Gonzalez, Frank J.
    Gyamfi, Maxwell A.
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2014, 289 (06) : 3244 - 3261
  • [40] Activation of pregnane X receptor induces hypercholesterolemia and accelerates atherosclerosis in mice
    Zhou, Changcheng
    Chen, Kwan Y.
    Breslow, Jan L.
    ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2008, 28 (06) : E32 - E32
12345