Investigating synergism of Mcl-1 inhibition with first line therapies for leukaemia

被引：0
|
作者：
Cosimo, E. [1 ]
Ball, R. J. [1 ]
Couves, A. [1 ]
Allan, E. K. [1 ]
Jorgensen, H. G. [1 ]
Michie, A. M. [1 ]
机构：
[1] Univ Glasgow, Inst Canc Sci, Paul OGorman Leukaemia Res Ctr, Glasgow, Lanark, Scotland
来源：
BRITISH JOURNAL OF HAEMATOLOGY | 2012年 / 157卷
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
148
引用
收藏
页码：57 / 58
页数：2
相关论文
共 50 条
  • [31] MEK/ERK and MCL-1 inhibition synergistically reverse apoptosis resistance in colon cancer cells with BRAF(V600E)-mediated MCL-1 upregulation
    Kawakami, Hisato
    Huang, Shengbing
    Sinicrope, Frank A.
    CANCER RESEARCH, 2016, 76
  • [32] Targeting MCL-1 sensitizes FLT3-ITD-positive leukemias to cytotoxic therapies
    Kasper, S.
    Breitenbuecher, F.
    Heidel, F.
    Hoffarth, S.
    Markova, B.
    Schuler, M.
    Fischer, T.
    BLOOD CANCER JOURNAL, 2012, 2 : e60 - e60
  • [33] Targeting MCL-1 sensitizes FLT3-ITD-positive leukemias to cytotoxic therapies
    S Kasper
    F Breitenbuecher
    F Heidel
    S Hoffarth
    B Markova
    M Schuler
    T Fischer
    Blood Cancer Journal, 2012, 2 : e60 - e60
  • [34] Mcl-1 is a novel therapeutic target for human sarcoma: synergistic inhibition of human sarcoma xenotransplants by a combination of Mcl-1 antisense Oligonucleotides with low-dose cyclophosphamide
    Thallinger, C
    Wolschek, MF
    Maierhofer, H
    Skvara, H
    Pehamberger, H
    Monia, BP
    Jansen, B
    Wacheck, V
    Selzer, E
    CLINICAL CANCER RESEARCH, 2004, 10 (12) : 4185 - 4191
  • [35] Combined Mcl-1 and YAP1/TAZ inhibition for treatment of metastatic uveal melanoma
    Glinkina, Kseniya A.
    Teunisse, Amina F. A. S.
    Gelmi, Maria Chiara
    de Vries, Jelle
    Jager, Martine J.
    Jochemsen, Aart G.
    MELANOMA RESEARCH, 2023, 33 (05) : 345 - 356
  • [36] Inhibition of cyclin E1 overcomes temozolomide resistance in glioblastoma by Mcl-1 degradation
    Liang, Huaxin
    Chen, Zhuo
    Sun, Libo
    MOLECULAR CARCINOGENESIS, 2019, 58 (08) : 1502 - 1511
  • [37] Inhibition of polo like kinase 1 in sarcomas induces apoptosis that is dependent on Mcl-1 suppression
    Nair, Jayasree S.
    Schwartz, Gary K.
    CELL CYCLE, 2015, 14 (19) : 3101 - 3111
  • [38] Activation of ATF4 mediates unwanted Mcl-1 accumulation by proteasome inhibition
    Hu, Jinsong
    Dang, Nana
    Menu, Eline
    De Bryune, Elke
    Xu, Dehui
    Van Camp, Ben
    Van Valckenborgh, Els
    Vanderkerken, Karin
    BLOOD, 2012, 119 (03) : 826 - 837
  • [39] Dual inhibition of the oncoproteins MCL-1 and BCL-2 by rationally designed polypharmacology
    Drennen, Brandon
    Hughes, Samuel
    Fletcher, Steven
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2017, 254
  • [40] Inhibition of the anti-apoptotic protein MCL-1 severely suppresses human hematopoiesis
    Bohler, Sheila
    Afreen, Sehar
    Fernandez-Orth, Juncal
    Demmerath, Eva-Maria
    Molnar, Christian
    Wu, Ying
    Weiss, Julia Miriam
    Mittapalli, Venugopal Rao
    Konstantinidis, Lukas
    Schmal, Hagen
    Kunze, Mirjam
    Erlacher, Miriam
    HAEMATOLOGICA, 2021, 106 (12) : 3136 - 3148
12345