A novel method for the preparation of a neurotoxic complex

被引:1
|
作者
Ryu, Bum Han [1 ]
Jang, Eunjin [1 ]
Ju, Hansol [1 ]
Kim, T. Doohun [1 ]
机构
[1] Ajou Univ, Dept Mol Sci & Technol, Grad Sch Interdisciplinary Programs, Suwon 443749, South Korea
关键词
Neurotoxicity; Apoptosis; FACS; ALPHA-LACTALBUMIN; AMYLOID FORMATION; OLEIC-ACID; SYNUCLEIN; PROTEIN; DISEASE;
D O I
10.1016/j.ab.2013.01.005
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Neurodegenerative diseases such as Alzheimer's disease (AD) and Parkinson's disease (PD) can be attributed to the specific degeneration of neuronal cells in the brain. However, the natures and action modes of toxic species remain largely unknown. Here, we present a simple and fast method for the preparation of neurotoxic complex with alpha-synuclein, which is implicated in PD. (c) 2013 Elsevier Inc. All rights reserved.
引用
收藏
页码:137 / 139
页数:3
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