Labdane diterpenes from Juniperus communis L. berries

被引:22
|
作者
Martin, AM [1 ]
Queiroz, EF [1 ]
Marston, A [1 ]
Hostettmann, K [1 ]
机构
[1] Univ Geneva, Lab Pharmacognosy & Phytochem, CH-1211 Geneva 4, Switzerland
关键词
centrifugal partition chromatography; diterpenes; Juniperus communis; Cupressaceae;
D O I
10.1002/pca.878
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
A phytochemical study of the methanol extract of Juniperus communis berries was undertaken. The crude extract was analysed by HPLC-UV and the isolation of the minor compounds was performed by centrifugal partition chromatography. By this means, five diterpenes were isolated, one of which was a new labdane diterpene 15,16-epoxy-12-hydroxy-8(17),13(16),14-labdatrien-19-oic acid. The structures of the isolated compounds were elucidated by spectroscopic methods, including UV, NMR, MS and HR-MS. Copyright (c) 2005 John Wiley & Sons, Ltd.
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页码:32 / 35
页数:4
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