Gut microbes, immunity, and spondyloarthritis

被引：35
|
作者：
Stoll, Matthew L. [1 ]
机构：
[1] Univ Alabama Birmingham, Birmingham, AL 35233 USA
来源：
CLINICAL IMMUNOLOGY | 2015年 / 159卷 / 02期
关键词：
Spondyloarthritis; Inflammatory bowel disease; Microbiota; Microbiome; INFLAMMATORY-BOWEL-DISEASE; EXCLUSIVE ENTERAL NUTRITION; ENTHESITIS-RELATED ARTHRITIS; INTESTINAL DENDRITIC CELLS; JUVENILE CHRONIC ARTHRITIS; OUTER-MEMBRANE PROTEIN; ANKYLOSING-SPONDYLITIS; CROHNS-DISEASE; SACCHAROMYCES-CEREVISIAE; PSORIATIC-ARTHRITIS;
D O I：
10.1016/j.clim.2015.05.001
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
The last decade has witnessed an explosion of studies evaluating the impact of the human microbiota on a variety of disease states. The microbiota can impact diseases in multiple ways, including through abnormalities in the diversity and contents of the microbiota, as well as by acting as targets of immunologic dysregulation. Herein, evidence that the microbiota in spondyloarthritis is both altered and abnormally targeted by the immune system will be presented. (C) 2015 Elsevier Inc. All rights reserved.
引用
收藏
页码：134 / 142
页数：9
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