Associations between adverse childhood experiences and clinical characteristics of eating disorders

被引:90
|
作者
Guillaume, S. [1 ,2 ]
Jaussent, I. [2 ]
Maimoun, L. [3 ,4 ]
Ryst, A. [1 ]
Seneque, M. [1 ,2 ]
Villain, L. [1 ]
Hamroun, D. [5 ]
Lefebvre, P. [6 ]
Renard, E. [6 ,7 ,8 ]
Courtet, Ph. [1 ,2 ]
机构
[1] CHRU Montpellier, Lapeyronie Hosp, Dept Psychiat Emergency & Acute Care, Montpellier, France
[2] Univ Montpellier, INSERM, U1061, Montpellier, France
[3] CHRU Montpellier, Hop Lapeyronie, Dept Med Nucl, Montpellier, France
[4] Univ Montpellier, CNRS, INSERM, Physiol & Med Expt Coeur & Muscles,U1046,UMR9214, Montpellier, France
[5] CHRU Montpellier, Direct Rech & Innovat, Montpellier, France
[6] Montpellier Univ Hosp, Dept Endocrinol, Diabet, Nutr, Montpellier, France
[7] Clin Invest Ctr 1411, INSERM, Montpellier, France
[8] Univ Montpellier, CNRS, Inst Funct Genom, UMR 5203,INSERM,U1191, Montpellier, France
来源
SCIENTIFIC REPORTS | 2016年 / 6卷
关键词
QUALITY-OF-LIFE; SEXUAL-ABUSE; PHYSICAL ABUSE; MEDIATIONAL SIGNIFICANCE; PSYCHIATRIC COMORBIDITY; EMOTIONAL ABUSE; BULIMIC WOMEN; TRAUMA; PSYCHOPATHOLOGY; MALTREATMENT;
D O I
10.1038/srep35761
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Patients with eating disorders (EDs) frequently report a history of childhood trauma (CT). We investigated whether certain subtypes of CT are associated with more severe features of EDs, independently of psychiatric comorbidity, and whether they act additively. One hundred and ninety-two patients with DSM-V-defined EDs were consecutively recruited. Five clinical characteristics were assessed: restraint, eating, shape and weight concerns on the EDE-Q, and daily functioning. CT was assessed by the childhood traumatism questionnaire. The clinical features were associated with at least one CT subtype (emotional, sexual or physical abuse, emotional neglect). Multivariate analyses adjusted for lifetime comorbid psychiatric disorders revealed that emotional abuse independently predicted higher eating, shape and weight concerns and lower daily functioning, whereas sexual and physical abuse independently predicted higher eating concern. A dose-effect relationship characterised the number of CT subtypes and the severity of the clinical features, suggesting a consistent and partly independent association between CT and more severe clinical and functional characteristics in EDs. Emotional abuse seems to have the most specific impact on ED symptoms. Last, not all CT subtypes have the same impact but they do act additively.
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页数:7
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