The Application of combination of External Drainage from Intestinal Cavity and Peritoneal Drainage on the Surgical Treatment for Neonates with Necrotizing Enterocolitis

Object: To evaluate the efficacy of combination of external drainage from intestinal cavity and peritoneal drainage on the surgical treatment for neonates with necrotizing enterocolitis(NEC). Methods: A retrospective analysis was conduct on 48 cases of newborns with extensive and multiple intestinal necrosis found intraoperatively, all of which could not accept firststage resected, treated by traditional operation, external drainage from intestinal cavity, peritoneal drainage and combination of external drainage from intestinal cavity and peritoneal drainage, between January, 2010 to January 2017. Duration of operation, amount of bleeding, and the survival rate after operation were compared among the four groups, which were divided by surgical methods. Results: No significant difference was observed in age, and gender (P>0.05) among the four groups. However, the duration of operation was significantly shorter, the amount of bleeding was significantly lessen, the survival rate was significantly higher in the patients of group B(external drainage from intestinal cavity), group C(peritoneal drainage) and group D(combination of external drainage from intestinal cavity and peritoneal drainage) than the patients of group A(traditional operation)(P<0.05). While the survival rate of group D was significantly higher than that of other groups. Conclusion: The combination of external drainage from intestinal cavity and peritoneal drainage can improve the survival rate of the NEC children more obviously than any other single methods.