The Clinical Implications of Thrombelastography in the Diagnosis of Acute Cerebral Infarction

被引:34
|
作者
Liang, Ying [1 ]
Wu, Jun [1 ]
Liu, Jianquan [1 ]
Liu, Hong [1 ]
Chen, Juan [1 ]
机构
[1] Gen Hosp Yangtze River Shipping, Dept Clin Lab, Wuhan, Hubei, Peoples R China
关键词
thrombelastography; acute cerebral infarction; coagulation tests; ACUTE ISCHEMIC-STROKE; MECHANICAL THROMBOLYSIS; INTRAARTERIAL UROKINASE; COAGULATION;
D O I
10.7754/Clin.Lab.2017.170803
中图分类号
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号
1001 ;
摘要
Background: Thrombelastography (TEG) is an analyzer reflecting the dynamic changes of blood coagulation. It has been used as a diagnosis index in many diseases. The aim of this study was to evaluate the relationship between TEG and acute cerebral infarction. Methods: Eighty patients with acute cerebral infarction and 80 healthy controls were enrolled. Each patient's TEG results and routine coagulation indices were recorded. All analyses were conducted with SPSS16.0 software. Results: Patients with acute cerebral infarction showed lower TEG R and K levels but higher TEG MA levels. There was a significantly negative correlation between TEG R and fibrinogen in the patient group. In addition, receiver operator characteristic curve analysis showed that TEG MA (cutoff value 63.9 mm) was a predictor of acute cerebral infarction (AUC value = 0.741, sensitivity 61%, specificity 81%). Conclusions: TEG results have important clinical implications in the early diagnosis of acute cerebral infarction.
引用
收藏
页码:147 / 152
页数:6
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