STEVIE (Safety Events In VIsmodEgib), a single-arm, open-label study on the safety of Hedgehog Pathway Inhibitors in advanced basal cell carcinoma Vismodegib: interim analysis of 150 patients

被引:0
|
作者
Gutzmer, Ralf [1 ]
Leverkues, Martin [2 ,3 ]
Garbe, Claus [4 ]
Herbst, Rudolf [5 ]
Schadendorf, Dirk [6 ]
Kunstfeld, Rainer [7 ]
Hansson, Johan [8 ]
Basset-Seguin, Nicole [9 ]
Page, Damian [10 ]
Mitchell, Lada [10 ]
Hauschild, Axel [11 ]
机构
[1] Hannover Med Sch, Hannover, Germany
[2] Univ Med Mannheim, Mannheim, Germany
[3] Univ Heidelberg, Med Fak Mannheim, D-6800 Mannheim, Germany
[4] Univ Klin Tubingen, Tubingen, Germany
[5] HELIOS Hauttumorzentrum, Erfurt, Germany
[6] Univ Klinikum Essen, Essen, Germany
[7] Med Univ Wien, Vienna, Austria
[8] Karolinska Univ Spital, Stockholm, Sweden
[9] Hop St Louis, Paris, France
[10] F Hoffmann La Roche & Cie AG, Basel, Switzerland
[11] Univ Klinikum Schleswig Holstein, Kiel, Germany
关键词
D O I
10.1111/j.1610-0387.2012.08008.x
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
引用
收藏
页码:677 / 677
页数:1
相关论文
共 50 条
  • [11] Vismodegib and Sonidegib in Locally Advanced and Metastatic Basal Cell Carcinoma: Update on Hedgehog Pathway Inhibitors
    Wijaya, J. Kurnia
    Djawad, K.
    Wahab, S.
    Nurdin, A.
    Anwar, A. Irawan
    ACTAS DERMO-SIFILIOGRAFICAS, 2022, 113 (05): : T443 - T450
  • [12] Expanded access study of patients with advanced basal cell carcinoma treated with the Hedgehog pathway inhibitor, vismodegib
    Chang, Anne Lynn S.
    Solomon, James A.
    Hainsworth, John D.
    Goldberg, Leonard
    McKenna, Edward
    Day, Bann-mo
    Chen, Diana M.
    Weiss, Glen J.
    JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2014, 70 (01) : 60 - 69
  • [13] Outcomes of Vismodegib for Periocular Locally Advanced Basal Cell Carcinoma From an Open-label Trial
    Ben Ishai, Meydan
    Tiosano, Alon
    Fenig, Eyal
    Ben Simon, Guy
    Yassur, Iftach
    JAMA OPHTHALMOLOGY, 2020, 138 (07) : 749 - 755
  • [14] An Open-Label, Phase II, Multicenter, Single-Arm Study of Induction and Concurrent Vismodegib Combined with Curative-Intent Radiation Therapy for Locally Advanced Basal Cell Carcinoma
    Yom, Sue
    Arron, Sarah
    Ho, Alan
    Algazi, Alain
    Dunn, Lara
    Tsai, C. Jillian
    Humphries, Audrey
    Hultman, Carter
    Grekin, Roy
    Knott, P. Daniel
    Barker, Christopher
    AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS, 2021, 44 (10): : S16 - S16
  • [15] A Pivotal Multicenter Trial Evaluating Efficacy and Safety of the Hedgehog Pathway Inhibitor (HPI) Vismodegib in Patients With Advanced Basal Cell Carcinoma (BCC)
    Dirix, L.
    Migden, M. R.
    Oro, A. E.
    Hauschild, A.
    Lewis, K.
    Mueller, A. B.
    Yauch, R.
    Reddy, J. C.
    Sekulic, A.
    EUROPEAN JOURNAL OF CANCER, 2011, 47 : 2 - 2
  • [16] An Investigator-Initiated Open-Label Trial of Sonidegib in Advanced Basal Cell Carcinoma Patients Resistant to Vismodegib
    Danial, Christina
    Sarin, Kavita Y.
    Oro, Anthony E.
    Chang, Anne Lynn S.
    CLINICAL CANCER RESEARCH, 2016, 22 (06) : 1325 - 1329
  • [17] Vismodegib in neoadjuvant treatment of locally advanced basal cell carcinoma: First results of a multicenter, open-label, phase 2 trial (VISMONEO study) Neoadjuvant Vismodegib in Locally Advanced Basal Cell Carcinoma
    Bertrand, Nicolas
    Guerreschi, Pierre
    Basset-Seguin, Nicole
    Saiag, Philippe
    Dupuy, Alain
    Dalac-Rat, Sophie
    Dziwniel, Veronique
    Depoortere, Cesar
    Duhamel, Alain
    Mortier, Laurent
    ECLINICALMEDICINE, 2021, 35
  • [18] Efficacy and safety of Vismodegib treatment in patients with advanced basal cell carcinoma and multiple comorbidities
    Spallone, Giulia
    Sollena, Pietro
    Ventura, Alessandra
    Fargnoli, Maria C.
    Gutierrez, Carlota
    Piccerillo, Alfredo
    Tambone, Sara
    Bianchi, Luca
    Peris, Ketty
    DERMATOLOGIC THERAPY, 2019, 32 (06)
  • [19] Safety and efficacy of vismodegib in patients aged ≥65 years with advanced basal cell carcinoma
    Chang, Anne Lynn S.
    Lewis, Karl D.
    Arron, Sarah T.
    Migden, Michael R.
    Solomon, James A.
    Yoo, Simon
    Day, Bann-Mo
    McKenna, Edward F.
    Sekulic, Aleksandar
    ONCOTARGET, 2016, 7 (46) : 76118 - 76124
  • [20] EFFICACY AND SAFETY OF THE HEDGEHOG PATHWAY INHIBITOR VISMODEGIB IN PATIENTS WITH ADVANCED BASAL CELL CARCINOMA (BCC): 12-MONTH ERIVANCE BCC STUDY UPDATE
    Sekulic, A.
    Migden, M. R.
    Oro, A.
    Lewis, K.
    Hainsworth, J. D.
    Yoo, S.
    Dirix, L.
    Hou, J.
    Yue, H.
    Hauschild, A.
    ANNALS OF ONCOLOGY, 2012, 23 : 362 - 362