Management of locoregional recurrence in cutaneous squamous cell carcinoma of the head and neck

被引:13
|
作者
Strassen, Ulrich [1 ]
Hofauer, Benedikt [1 ]
Jacobi, Christian [2 ]
Knopf, Andreas [1 ]
机构
[1] Klinikum Rechts Der Isar, Otorhinolaryngol Head & Neck Surg, Ismaningerstr 22, D-81675 Munich, Germany
[2] Klinikum Grosshadern, Otorhinolaryngol Head & Neck Surg, Munich, Germany
关键词
Cutaneous squamous cell carcinoma; Head and neck; Outcome; Therapy; Recurrence; LYMPH-NODE METASTASIS; NONMELANOMA SKIN-CANCER; RISK-FACTORS; EPIDEMIOLOGY; MELANOMA;
D O I
10.1007/s00405-016-4243-7
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
Cutaneous squamous cell carcinomas often affect elderly patients. Follow-up monitoring is difficult in these patients due to their multi-morbidity and reduced compliance. Tumour recurrence is consequently diagnosed in advanced tumour stages. Surgical therapy with curative intention often requires extended resections. The study at hand should determine whether surgical concepts are warranted in this collective. Sixty-seven patients who underwent surgical procedure due to recurrent disease of cutaneous head and neck squamous cell carcinoma were included. The cohort was divided in patients with/without adjuvant therapeutic regimens. Data were assessed retrospectively. Complete tumour resection was achieved in 85 % of our patients. Patients with adjuvant treatment demonstrated a favorable 5-year-recurrence-free interval (78 vs 30 %) and overall survival (79 vs 46 %). Complete surgical resection of advanced recurrent head and neck cutaneous squamous cell carcinomas is possible and yields favorable results in terms of survival, especially if combined with adjuvant treatment.
引用
收藏
页码:501 / 506
页数:6
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