Design and bioanalytical applications of DNA hairpin-based fluorescent probes

被引：40
|
作者：
Huang, Jin [1 ]
Yang, Xiaohai [1 ]
He, Xiaoxiao [1 ]
Wang, Kemin [1 ]
Liu, Jianbo [1 ]
Shi, Hui [1 ]
Wang, Qing [1 ]
Guo, Qiuping [1 ]
He, Dinggeng [1 ]
机构：
[1] Hunan Univ, State Key Lab Chemo Biosensing & Chemometr, Coll Chem & Chem Engn, Coll Biol,Key Lab Bionanotechnol & Mol Engn Hunan, Changsha 410082, Hunan, Peoples R China
来源：
TRAC-TRENDS IN ANALYTICAL CHEMISTRY | 2014年 / 53卷
基金：
中国国家自然科学基金;
关键词：
Aptamer; Bioanalytical application; Biosensor; DNA hairpin; DNA hairpin-based fluorescent probe (DHFP); Dye molecule; Fluorescent probe; Molecular beacon (MB); Nanomaterial; Signal transduction; MOLECULAR BEACONS; NUCLEIC-ACIDS; GRAPHENE OXIDE; EXCIMER PROBES; PROTEIN; HYBRIDIZATION;
D O I：
10.1016/j.trac.2013.08.007
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
DNA hairpin-based fluorescent probes (DHFPs) are widely used in molecular biology, biosensor development, mRNA monitoring in living cells and imaging in vivo. In this review, we focus on the typical designs and the recent bioanalytical applications of DHEPs. We describe the application of different materials with excellent photophysical properties as signal labels to reduce the background and to increase the brightness of the DHFPs. These labels range from dye molecules to nanomaterials. We also discuss the general design of signal-transduction mechanisms. (C) 2013 Elsevier Ltd. All rights reserved.
引用
收藏
页码：11 / 20
页数：10
相关论文
共 50 条
  • [31] Rational design of small molecule fluorescent probes for biological applications
    Jun, Joomyung, V
    Chenoweth, David M.
    Petersson, E. James
    ORGANIC & BIOMOLECULAR CHEMISTRY, 2020, 18 (30) : 5747 - 5763
  • [32] Fluorescent probes for targeting the Golgi apparatus: design strategies and applications
    Xu, Silin
    Yan, Kai-Cheng
    Xu, Zhi-Hong
    Wang, Yuan
    James, Tony D.
    CHEMICAL SOCIETY REVIEWS, 2024, 53 (14) : 7590 - 7631
  • [33] Fluorescent probes for targeting endoplasmic reticulum: design strategies and their applications
    Singh, Deepmala
    Rajput, Deeksha
    Kanvah, Sriram
    CHEMICAL COMMUNICATIONS, 2022, 58 (15) : 2413 - 2429
  • [34] Recent advances in the fluorescent probes for flavinase activity: design and applications
    Yang, Yiting
    Zhai, Hongchen
    Yuan, Jie
    Wang, Kui
    Zhang, Hua
    CHEMISTRY-AN ASIAN JOURNAL, 2022, 17 (07)
  • [35] DNA-based bioanalytical microsystems for handheld device applications
    Lee, TMH
    Hsing, IM
    ANALYTICA CHIMICA ACTA, 2006, 556 (01) : 26 - 37
  • [36] Huntingtin exon 1 fibrils feature an interdigitated β-hairpin-based polyglutamine core
    Hoop, Cody L.
    Lin, Hsiang-Kai
    Kar, Karunakar
    Magyarfalvi, Gabor
    Lamley, Jonathan M.
    Boatz, Jennifer C.
    Mandal, Abhishek
    Lewandowski, Jozef R.
    Wetzel, Ronald
    van der Wel, Patrick C. A.
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2016, 113 (06) : 1546 - 1551
  • [37] Dual Sensing of Hairpin and Quadruplex DNA Structures Using Multicolored Peptide Nucleic Acid Fluorescent Probes
    Koripelly, Girish
    Meguellati, Kamel
    Ladame, Sylvain
    BIOCONJUGATE CHEMISTRY, 2010, 21 (11) : 2103 - 2109
  • [38] Naphthalenedicarboxamides as fluorescent probes of inter- and intramolecular electron transfer in single strand, hairpin, and duplex DNA
    Lewis, FD
    Zhang, YF
    Liu, XY
    Xu, N
    Letsinger, RL
    JOURNAL OF PHYSICAL CHEMISTRY B, 1999, 103 (13): : 2570 - 2578
  • [39] Fluorescent Probes of DNA Repair
    Wilson, David L.
    Kool, Eric T.
    ACS CHEMICAL BIOLOGY, 2018, 13 (07) : 1721 - 1733
  • [40] Chalcogen-based fluorescent probes for metal ion detection: Principles, applications, and design strategies
    Liu, Yuning
    Zhang, Yandong
    Jiang, Xiaowei
    An, Jing
    Dai, Jiyun
    Ying, Ying
    Li, Runhang
    Wang, Weihong
    Liu, Li
    Wu, Hongxin
    COORDINATION CHEMISTRY REVIEWS, 2024, 513
12345