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- [31] First-in human, phase 1, dose-escalation pharmacokinetic and pharmacodynamic study of the oral dual PI3K and mTORC1/2 inhibitor PQR309 in patients with advanced solid tumors (SAKK 67/13)EUROPEAN JOURNAL OF CANCER, 2018, 96 : 6 - 16Wicki, Andreas论文数: 0 引用数: 0 h-index: 0机构: Univ Hosp Basel, Div Oncol, Dept Biomed, Petersgraben 4, CH-4031 Basel, Switzerland Univ Hosp Basel, Div Oncol, Dept Biomed, Petersgraben 4, CH-4031 Basel, SwitzerlandBrown, Nicholas论文数: 0 引用数: 0 h-index: 0机构: Univ Coll London Hosp NHS Trust, Gynecol Oncol Team, 235 Euston Rd, London NW1 2BU, England Univ Hosp Basel, Div Oncol, Dept Biomed, Petersgraben 4, CH-4031 Basel, SwitzerlandXyrafas, Alexandros论文数: 0 引用数: 0 h-index: 0机构: SAKK Coordinating Ctr, Effingerstr 33, CH-3008 Bern, Switzerland Univ Hosp Basel, Div Oncol, Dept Biomed, Petersgraben 4, CH-4031 Basel, SwitzerlandBize, Vincent论文数: 0 引用数: 0 h-index: 0机构: SAKK Coordinating Ctr, Effingerstr 33, CH-3008 Bern, Switzerland Univ Hosp Basel, Div Oncol, Dept Biomed, Petersgraben 4, CH-4031 Basel, SwitzerlandHawle, Hanne论文数: 0 引用数: 0 h-index: 0机构: SAKK Coordinating Ctr, Effingerstr 33, CH-3008 Bern, Switzerland Univ Hosp Basel, Div Oncol, Dept Biomed, Petersgraben 4, CH-4031 Basel, SwitzerlandBerardi, Simona论文数: 0 引用数: 0 h-index: 0机构: SAKK Coordinating Ctr, Effingerstr 33, CH-3008 Bern, Switzerland Univ Hosp Basel, Div Oncol, Dept Biomed, Petersgraben 4, CH-4031 Basel, SwitzerlandCmiljanovic, Natasa论文数: 0 引用数: 0 h-index: 0机构: Piqur Therapeut AG, Hochbergstr 60C, CH-4057 Basel, Switzerland Univ Hosp Basel, Div Oncol, Dept Biomed, Petersgraben 4, CH-4031 Basel, SwitzerlandCmiljanovic, Vladimir论文数: 0 引用数: 0 h-index: 0机构: Piqur Therapeut AG, Hochbergstr 60C, CH-4057 Basel, Switzerland Univ Hosp Basel, Div Oncol, Dept Biomed, Petersgraben 4, CH-4031 Basel, SwitzerlandStumm, Michael论文数: 0 引用数: 0 h-index: 0机构: Piqur Therapeut AG, Hochbergstr 60C, CH-4057 Basel, Switzerland Univ Hosp Basel, Div Oncol, Dept Biomed, Petersgraben 4, CH-4031 Basel, SwitzerlandDimitrijevic, Sasa论文数: 0 引用数: 0 h-index: 0机构: Piqur Therapeut AG, Hochbergstr 60C, CH-4057 Basel, Switzerland Univ Hosp Basel, Div Oncol, Dept Biomed, Petersgraben 4, CH-4031 Basel, SwitzerlandHerrmann, Richard论文数: 0 引用数: 0 h-index: 0机构: Piqur Therapeut AG, Hochbergstr 60C, CH-4057 Basel, Switzerland Univ Hosp Basel, Div Oncol, Dept Biomed, Petersgraben 4, CH-4031 Basel, SwitzerlandPretre, Vincent论文数: 0 引用数: 0 h-index: 0机构: Univ Hosp Basel, Dept Biomed, Petersgraben 4, CH-4031 Basel, Switzerland Univ Hosp Basel, Div Oncol, Dept Biomed, Petersgraben 4, CH-4031 Basel, SwitzerlandRitschard, Reto论文数: 0 引用数: 0 h-index: 0机构: Univ Hosp Basel, Dept Biomed, Petersgraben 4, CH-4031 Basel, Switzerland Univ Hosp Basel, Div Oncol, Dept Biomed, Petersgraben 4, CH-4031 Basel, SwitzerlandTzankov, Alexandar论文数: 0 引用数: 0 h-index: 0机构: Univ Hosp Basel, Dept Pathol, Schonbeinstr 40, CH-4056 Basel, Switzerland Univ Hosp Basel, Div Oncol, Dept Biomed, Petersgraben 4, CH-4031 Basel, SwitzerlandHess, Viviane论文数: 0 引用数: 0 h-index: 0机构: Univ Hosp Basel, Div Oncol, Dept Biomed, Petersgraben 4, CH-4031 Basel, Switzerland Univ Hosp Basel, Div Oncol, Dept Biomed, Petersgraben 4, CH-4031 Basel, SwitzerlandChilds, Alexa论文数: 0 引用数: 0 h-index: 0机构: Univ Coll London Hosp NHS Trust, Gynecol Oncol Team, 235 Euston Rd, London NW1 2BU, England Univ Hosp Basel, Div Oncol, Dept Biomed, Petersgraben 4, CH-4031 Basel, SwitzerlandHierro, Cinta论文数: 0 引用数: 0 h-index: 0机构: Univ Autonoma Barcelona, Vall dHebron Inst Oncol, Passeig Vall dHebron 119-129, Barcelona 08035, Spain Univ Hosp Basel, Div Oncol, Dept Biomed, Petersgraben 4, CH-4031 Basel, SwitzerlandRodon, Jordi论文数: 0 引用数: 0 h-index: 0机构: Univ Autonoma Barcelona, Vall dHebron Inst Oncol, Passeig Vall dHebron 119-129, Barcelona 08035, Spain Univ Hosp Basel, Div Oncol, Dept Biomed, Petersgraben 4, CH-4031 Basel, SwitzerlandHess, Dagmar论文数: 0 引用数: 0 h-index: 0机构: Cantonal Hosp St Gallen, Dept Hematol & Oncol, Rorschacherstr 95, CH-9007 St Gallen, Switzerland Univ Hosp Basel, Div Oncol, Dept Biomed, Petersgraben 4, CH-4031 Basel, SwitzerlandJoerger, Markus论文数: 0 引用数: 0 h-index: 0机构: Cantonal Hosp St Gallen, Dept Hematol & Oncol, Rorschacherstr 95, CH-9007 St Gallen, Switzerland Univ Hosp Basel, Div Oncol, Dept Biomed, Petersgraben 4, CH-4031 Basel, Switzerlandvon Moos, Roger论文数: 0 引用数: 0 h-index: 0机构: Cantonal Hosp Graubunden, Dept Hematol & Oncol, Loestr 170, CH-7000 Chur, Switzerland Univ Hosp Basel, Div Oncol, Dept Biomed, Petersgraben 4, CH-4031 Basel, SwitzerlandSessa, Cristiana论文数: 0 引用数: 0 h-index: 0机构: Osped San Giovanni Bellinzona, Ist Oncol Svizzera Italiana, CH-6500 Bellinzona, Switzerland Univ Hosp Basel, Div Oncol, Dept Biomed, Petersgraben 4, CH-4031 Basel, SwitzerlandKristeleit, Rebecca论文数: 0 引用数: 0 h-index: 0机构: Univ Coll London Hosp NHS Trust, Gynecol Oncol Team, 235 Euston Rd, London NW1 2BU, England Univ Hosp Basel, Div Oncol, Dept Biomed, Petersgraben 4, CH-4031 Basel, Switzerland
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- [33] A Phase lb Study Evaluating Safety, Tolerability, Pharmacokinetics (PK), and Activity of the Phosphoinositide-3 Kinase (PI3K) Inhibitor GDC-0941 in Combination with Trastuzumab-MCC-DM1 (T-DM1) in Patients with Advanced HER2-Positive Breast CancerCANCER RESEARCH, 2010, 70Krop, I. E.论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA 02115 USAWolff, A. C.论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA 02115 USAWiner, E. P.论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA 02115 USAMiller, K. D.论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA 02115 USAPark, B. H.论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA 02115 USAWare, J.论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA 02115 USAHolden, S.论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA 02115 USALevy, G. G.论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA 02115 USADerynck, M.论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA 02115 USAStorniolo, A. M.论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA 02115 USA
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- [37] A Multi-arm Phase 1 Dose Escalation Study of Safety, Pharmacokinetics, and Pharmacodynamics of the Dual PI3K/mTOR Inhibitors PF-04691502 (oral) and PF-05212384 (IV) in Combination with the MEK Inhibitor PD-0325901 or Irinotecan in Patients with Advanced CancerEUROPEAN JOURNAL OF CANCER, 2012, 48 : 109 - 109Britten, C.论文数: 0 引用数: 0 h-index: 0机构: Univ Calif Los Angeles, David Geffen Sch Med, Santa Monica, CA USA Univ Calif Los Angeles, David Geffen Sch Med, Santa Monica, CA USAWainberg, Z.论文数: 0 引用数: 0 h-index: 0机构: Univ Calif Los Angeles, David Geffen Sch Med, Santa Monica, CA USA Univ Calif Los Angeles, David Geffen Sch Med, Santa Monica, CA USATabernero, J.论文数: 0 引用数: 0 h-index: 0机构: Vall dHebron Univ, Dept Med Oncol, Barcelona, Spain Univ Calif Los Angeles, David Geffen Sch Med, Santa Monica, CA USAAlsina Maqueda, M.论文数: 0 引用数: 0 h-index: 0机构: Vall dHebron Univ, Dept Med Oncol, Barcelona, Spain Univ Calif Los Angeles, David Geffen Sch Med, Santa Monica, CA USALeong, S.论文数: 0 引用数: 0 h-index: 0机构: Univ Colorado, Div Med Oncol, Denver, CO 80202 USA Univ Calif Los Angeles, David Geffen Sch Med, Santa Monica, CA USASessa, C.论文数: 0 引用数: 0 h-index: 0机构: Univ Milan, Osped San Raffaele, Dept Med Oncol, I-20127 Milan, Italy Univ Calif Los Angeles, David Geffen Sch Med, Santa Monica, CA USAMillham, R.论文数: 0 引用数: 0 h-index: 0机构: Pfizer Inc, Pfizer Oncol, Groton, CT 06340 USA Univ Calif Los Angeles, David Geffen Sch Med, Santa Monica, CA USAGallo, J.论文数: 0 引用数: 0 h-index: 0机构: Pfizer, Pfizer Oncol, Milan, Italy Univ Calif Los Angeles, David Geffen Sch Med, Santa Monica, CA USASiu, L.论文数: 0 引用数: 0 h-index: 0机构: Princess Margaret Hosp, Div Med Oncol & Hematol, Toronto, ON M4X 1K9, Canada Univ Calif Los Angeles, David Geffen Sch Med, Santa Monica, CA USABrana, I.论文数: 0 引用数: 0 h-index: 0机构: Princess Margaret Hosp, Div Med Oncol & Hematol, Toronto, ON M4X 1K9, Canada Univ Calif Los Angeles, David Geffen Sch Med, Santa Monica, CA USA
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