High length-diameter ratio nanotubes self-assembled from a facial cyclopeptide

被引:14
|
作者
Qin, Si-Yong
Jiang, Hua-Fang
Liu, Xiang-Ji
Pei, Yi
Cheng, Han [1 ]
Sun, Yun-Xia
Zhang, Xian-Zheng
机构
[1] Wuhan Univ, Key Lab Biomed Polymers, Minist Educ, Wuhan 430072, Peoples R China
基金
中国国家自然科学基金;
关键词
SURFACTANT-LIKE PEPTIDES; SUPRAMOLECULAR HYDROGELS; FORM NANOTUBES; NANOSTRUCTURES; NANOVESICLES; MICROTUBES; DESIGN;
D O I
10.1039/c3sm52730a
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
A six-residue facial cyclopeptide was designed with the following sequence: c-[D-Leu-L-Lys-D-Ala-L-Lys-D-Leu-L-Gln] (CP). Extensive hydrogen bonding between the cyclopeptide backbones mainly regulated CP to self-assemble into single-walled nanotubes. Simultaneously, the hydrophobic interaction among facial hydrophobic side chains of CP was introduced to stabilize the hydrogen bonding, resulting in the formation of the thick-walled nanotubes with high length-diameter ratios.
引用
收藏
页码:947 / 951
页数:5
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