What are the reasons for low use of graphene quantum dots in immunosensing of cancer biomarkers?

被引：56
|
作者：
Hasanzadeh, Mohammad [1 ,2 ]
Shadjou, Nasrin [3 ,4 ]
机构：
[1] Tabriz Univ Med Sci, Drug Appl Res Ctr, Tabriz 51664, Iran
[2] Tabriz Univ Med Sci, Pharmaceut Anal Res Ctr, Tabriz 51664, Iran
[3] Urmia Univ, Nano Technol Res Ctr, Dept Nanochem, Orumiyeh, Iran
[4] Urmia Univ, Fac Sci, Dept Nanochem, Orumiyeh, Iran
来源：
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS | 2017年 / 71卷
关键词：
Graphene quantum dots; Immunosensor; Cancer; Biomarkers; Nanoparticle; PROSTATE-SPECIFIC ANTIGEN; GLASSY-CARBON ELECTRODE; SURFACE-PLASMON RESONANCE; ULTRASENSITIVE ELECTROCHEMICAL IMMUNOSENSOR; SELF-ASSEMBLED MONOLAYER; SCREEN-PRINTED ELECTRODE; VIRUS SUBGROUP-J; CARCINOEMBRYONIC ANTIGEN; LABEL-FREE; GOLD NANOPARTICLES;
D O I：
10.1016/j.msec.2016.11.068
中图分类号：
TB3 [工程材料学]; R318.08 [生物材料学];
学科分类号：
0805 ; 080501 ; 080502 ;
摘要：
Graphene quantum dots-based immunosensors have recently gained importance for detecting antigens and biomarkers responsible for cancer diagnosis, This paper reports a literature survey of the applications of graphene quantum dots for sensing cancer biomarkers. The survey sought to explore three questions; (1) Do graphene quantum dots improve immunosensing technology? (2) If so, can graphene quantum dots have a critical, positive impact on construction of immuno-devices? Ahd (3) What is the reason for some troubles in the application of this technology? The number of published papers in the field seems positively answer the first two questions. However additional efforts must be made to move from the bench to the real diagnosis. Some approaches to improve the analytical performance of graphene quantum dots-based immunosensors through their figures of merit have been also discussed. (C) 2016 Elsevier B.V. All rights reserved.
引用
收藏
页码：1313 / 1326
页数：14
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