4-alkyl-6-amino-4-N3,N5-diaryl-2-thioxo-1,2,3,4-tetrahydropyridine-3,5-dicarboxamides: I. Tandem synthesis and alkylation. Molecular and crystal structure of 6-allylsulfanyl-2-amino-4-isobutyl-N3,N5-di-m-tolyl-3,4-dihydropyridine-3,5-dicarboxamide

被引：4
|
作者：
Dyachenko, V. D. [1 ]
Karpov, E. N. [1 ]
机构：
[1] Shevchenko Lugansk Natl Univ, UA-91011 Lugansk, Ukraine
来源：
RUSSIAN JOURNAL OF GENERAL CHEMISTRY | 2013年 / 83卷 / 07期
关键词：
Mass Spectrum; EtOH; General Chemistry; White Powder; Yellow Powder;
D O I：
10.1134/S1070363213070153
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
4-Alkyl-6-amino-4-N (3),N (5)-diaryl-2-thioxo-1,2,3,4-tetrahydropyridine-3,5-dicarboxamides were obtained via tandem synthesis involving the Knoevenagel reaction, Michael reaction and intramolecular condensation. Alkylation of the obtained dicarboxamides proceeds regioselectively at the S atom to form the corresponding thioethers. Structure of 6-allylsulfanyl-2-amino-4-isobutyl-N (3),N (5)-di-m-tolyl-3,4-dihydropyridine-3,5-dicarboxamide was uniquely determined by XRD analysis.
引用
收藏
页码：1394 / 1401
页数：8
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