4-alkyl-6-amino-4-N3,N5-diaryl-2-thioxo-1,2,3,4-tetrahydropyridine-3,5-dicarboxamides: I. Tandem synthesis and alkylation. Molecular and crystal structure of 6-allylsulfanyl-2-amino-4-isobutyl-N3,N5-di-m-tolyl-3,4-dihydropyridine-3,5-dicarboxamide

被引：4

作者：

Dyachenko, V. D. ^{[1
]}

Karpov, E. N. ^{[1
]}

机构：

[1] Shevchenko Lugansk Natl Univ, UA-91011 Lugansk, Ukraine

来源：

RUSSIAN JOURNAL OF GENERAL CHEMISTRY | 2013年 / 83卷 / 07期

关键词：

Mass Spectrum; EtOH; General Chemistry; White Powder; Yellow Powder;

D O I：

10.1134/S1070363213070153

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

4-Alkyl-6-amino-4-N (3),N (5)-diaryl-2-thioxo-1,2,3,4-tetrahydropyridine-3,5-dicarboxamides were obtained via tandem synthesis involving the Knoevenagel reaction, Michael reaction and intramolecular condensation. Alkylation of the obtained dicarboxamides proceeds regioselectively at the S atom to form the corresponding thioethers. Structure of 6-allylsulfanyl-2-amino-4-isobutyl-N (3),N (5)-di-m-tolyl-3,4-dihydropyridine-3,5-dicarboxamide was uniquely determined by XRD analysis.

引用

页码：1394 / 1401

页数：8

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