Susceptibility to Melaleuca alternifolia (tea tree) oil of yeasts isolated from the mouths of patients with advanced cancer

被引：27

作者：

Bagg, Jeremy

Jackson, Margaret S.

Sweeney, M. Petrina

Ramage, Gordon

Davies, Andrew N.

机构：

[1] Univ Glasgow, Sch Dent, Glasgow G2 3JZ, Lanark, Scotland

[2] Glasgow Caledonian Univ, Glasgow G4 0BA, Lanark, Scotland

[3] Royal Marsden Hosp, Dept Palliat Med, Sutton SM2 5PT, Surrey, England

来源：

ORAL ONCOLOGY | 2006年 / 42卷 / 05期

关键词：

yeasts; oral infection; cancer; tea tree oil;

D O I：

10.1016/j.oraloncology.2005.10.002

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Yeasts that are resistant to azole antifungal drugs are increasingly isolated from the mouths of cancer patients suffering from oral fungal infections. Tea tree oil is an agent possessing antimicrobial properties that may prove useful in the prevention and management of infections caused by these organisms. In this study, 301 yeasts isolated from the mouths of 199 patients suffering from advanced cancer were examined by an in vitro agar dilution assay for susceptibility to tea tree oil. All of the isolates tested were susceptible, including 41 that were known to be resistant to both fluconazole and itraconazote. Clinical studies of tea tree oil as an agent for the prevention and treatment of oral fungal infections in immunocompromised patients merit consideration. (c) 2005 Elsevier Ltd. All rights reserved.

引用

页码：487 / 492

页数：6

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