FDG-PET Response-adapted Therapy Is 18F-Fluorodeoxyglucose Positron Emission Tomography a Safe Predictor for a Change of Therapy?

被引：8
|
作者：
Hutchings, Martin [1 ]
机构：
[1] Rigshosp, Dept Haematol, DK-2100 Copenhagen, Denmark
来源：
HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA | 2014年 / 28卷 / 01期
关键词：
FDG-PET; PET/CT; Interim; Hodgkin; Lymphoma; Response adapted; UNFAVORABLE HODGKINS LYMPHOMA; CLINICAL-PRACTICE GUIDELINES; INVOLVED-FIELD RADIOTHERAPY; STEM-CELL TRANSPLANTATION; EVENT-FREE SURVIVAL; F-18-FDG PET; INTERIM-PET; CYCLES; INTERNATIONAL WORKSHOP; FINAL ANALYSIS;
D O I：
10.1016/j.hoc.2013.10.008
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT) is the most accurate tool for staging, treatment monitoring, and response evaluation in Hodgkin lymphoma (HL). Early determination of treatment sensitivity by FDG-PET is the best tool to guide individualized, response-adapted treatment. Several ongoing or recently completed trials have investigated the use of FDG-PET/CT for early response-adapted HL therapy. The results are encouraging, but the data are immature, and PET response-adapted HL therapy is discouraged outside the setting of clinical trials. PET/CT looks promising for selection of therapy in relapsed and refractory disease, but the role in this setting is still unclear.
引用
收藏
页码：87 / +
页数：18
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