Isolation of tumor cells from peripheral blood - comparison of PCR and immunochemistry

被引:0
|
作者
Illert, B [1 ]
Horak, KH [1 ]
Timmermann, W [1 ]
Otto, C [1 ]
Thiede, A [1 ]
机构
[1] Univ Wurzburg, Dept Surg, D-97070 Wurzburg, Germany
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中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Detection of tumor cells is discussed as a prognostic marker in malignant disease. Two different methods for detection of tumor cells from peripheral venous blood were compared using the polymerase-chain-reaction and immunochemistry. With both methods tumor cells can be detected in concentrations up to 10 cells/five mi of blood. Combination of both methods facilitates high sensitivity and visual proof of tumor cells in vitro. Attempt, method and benefit of this approach must be proofed concerning a definite clinical use.
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页码:195 / 197
页数:3
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