Adhesion of membranes with active stickers -: art. no. 048101

被引：28

作者：

Rózycki, B ^{[1
]}

Lipowsky, R

Weikl, TR

机构：

[1] Max Planck Inst Colloids & Interfaces, D-14424 Potsdam, Germany

[2] Univ Warsaw, Inst Theoret Phys, PL-00681 Warsaw, Poland

来源：

PHYSICAL REVIEW LETTERS | 2006年 / 96卷 / 04期

关键词：

D O I：

10.1103/PhysRevLett.96.048101

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

We consider a theoretical model for membranes with adhesive receptors, or stickers, that are actively switched between two conformational states. In their "on" state, the stickers bind to ligands in an apposing membrane, whereas they do not interact with the ligands in their "off" state. We show that the adhesiveness of the membranes depends sensitively on the rates of the conformational switching process. This dependence is reflected in a resonance at intermediate switching rates, which can lead to large membrane separations and unbinding. Our results may provide insights into novel mechanisms for the controlled adhesion of biological or biomimetic membranes.

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页数：4

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