Long-term evaluation of lipid profile and oral glucose tolerance test in Norplant® users

被引：1
|
作者：
Araujo, FF [1 ]
de Lima, GR [1 ]
Guazzelli, CAF [1 ]
Barbieri, M [1 ]
Vigorito, NM [1 ]
Lindsey, PC [1 ]
Baracat, EC [1 ]
机构：
[1] Univ Fed Sao Paulo, Dept Obstet & Gynecol, Escola Paulista Med, Sao Paulo, Brazil
来源：
CONTRACEPTION | 2006年 / 73卷 / 04期
关键词：
levonorgestrel; subdermal contraceptive; Norplant (R); cholesterol; lipids; OGTT; diabetes;
D O I：
10.1016/j.contraception.2005.10.018
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
Purpose: This Study reports the results of the lipid profile and oral glucose tolerance test (OGTT) in 46 normal patients tested before and after 5 years of Norplant use. Results: After 5 years, there was a Substantial decrease of 28.9% in high-density lipoprotein cholesterol levels and a similar but less pronounced fall of 7.1% in the total cholesterol levels. The Castelli 1 index did not vary, and the triglycerides and low-density lipoprotein cholesterol levels remained normal and unchanged throughout the study period. All the mean values of OGTT were significantly lower after 5 years, except for the 90-min glycemia. Conclusion: These findings indicate that long-term Norplant use does not increase cardiovascular risks. (c) 2006 Elsevier Inc. All rights reserved.
引用
收藏
页码：361 / 363
页数：3
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