Crucial role of the small GTPase Rac1 in insulin-stimulated translocation of glucose transporter 4 to the mouse skeletal muscle sarcolemma

被引:0
|
作者
Ued, S.
Kitazawa, S.
Ishida, K.
Nishikawa, Y.
Matsui, M.
Matsumoto, H.
Aoki, T.
Nozaki, S.
Takeda, T.
Tamori, Y. [1 ]
Aiba, A. [2 ]
Kahn, C. [3 ]
Kataoka, T.
Satoh, T.
机构
[1] Kobe Univ, Grad Sch Med, Div Diabet Metab & Endocrinol, Kobe, Hyogo 657, Japan
[2] Kobe Univ, Grad Sch Med, Div Mol Genet, Kobe, Hyogo 657, Japan
[3] Harvard Univ, Sch Med, Joslin Diabet Ctr, Boston, MA 02115 USA
关键词
D O I
暂无
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
618
引用
收藏
页数:1
相关论文
共 50 条
  • [21] Rac1 governs exercise-stimulated glucose uptake in skeletal muscle through regulation of GLUT4 translocation in mice
    Sylow, Lykke
    Nielsen, Ida L.
    Kleinert, Maximilian
    Moller, Lisbeth L. V.
    Ploug, Thorkil
    Schjerling, Peter
    Bilan, Philip J.
    Klip, Amira
    Jensen, Thomas E.
    Richter, Erik A.
    JOURNAL OF PHYSIOLOGY-LONDON, 2016, 594 (17): : 4997 - 5008
  • [22] Role for RalA downstream of Rac1 in skeletal muscle insulin signalling
    Takenaka, Nobuyuki
    Sumi, Yukio
    Matsuda, Keiko
    Fujita, Junko
    Hosooka, Tetsuya
    Noguchi, Tetsuya
    Aiba, Atsu
    Satoh, Takaya
    BIOCHEMICAL JOURNAL, 2015, 469 : 445 - 454
  • [23] Syntaxin 4 is required for skeletal muscle insulin-stimulated glucose transport in vivo
    Yang, C
    Coker, KJ
    Kim, J
    Mora, S
    Thurmond, DC
    Shulman, GI
    Pessin, JE
    DIABETES, 2001, 50 : A524 - A524
  • [24] Impaired insulin-stimulated glucose transport in ATM-deficient mouse skeletal muscle
    Ching, James Kain
    Spears, Larry D.
    Armon, Jennifer L.
    Renth, Allyson L.
    Andrisse, Stanley
    Collins, Roy L.
    Fisher, Jonathan S.
    APPLIED PHYSIOLOGY NUTRITION AND METABOLISM, 2013, 38 (06) : 589 - 596
  • [25] Rac1 Is a Novel Regulator of Contraction-Stimulated Glucose Uptake in Skeletal Muscle
    Sylow, Lykke
    Jensen, Thomas E.
    Kleinert, Maximilian
    Mouatt, Joshua R.
    Maarbjerg, Stine J.
    Jeppesen, Jacob
    Prats, Clara
    Chiu, Tim T.
    Boguslavsky, Shlomit
    Klip, Amira
    Schjerling, Peter
    Richter, Erik A.
    DIABETES, 2013, 62 (04) : 1139 - 1151
  • [26] Overexpression of the glucose transporter GLUT4 in adipose cells interferes with insulin-stimulated translocation
    Al-Hasani, H
    Yver, DR
    Cushman, SW
    FEBS LETTERS, 1999, 460 (02) : 338 - 342
  • [27] Dissociation of GLUT4 translocation and insulin-stimulated glucose transport in transgenic mice overexpressing GLUT1 in skeletal muscle
    Hansen, PA
    Wang, WC
    Marshall, BA
    Holloszy, JO
    Mueckler, M
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (29) : 18173 - 18179
  • [28] Disruption of cortical actin in intact skeletal muscle inhibits insulin-stimulated GLUT4 translocation and glucose transport
    Brozinick, JT
    Hawkins, E
    Misener, E
    Strawbridge, A
    Elmendorf, J
    DIABETES, 2004, 53 : A55 - A55
  • [29] Rac1 muscle knockout exacerbates the detrimental effect of high-fat diet on insulin-stimulated muscle glucose uptake independently of Akt
    Raun, Steffen H.
    Ali, Mona
    Kjobsted, Rasmus
    Moller, Lisbeth L. V.
    Federspiel, Morten A.
    Richter, Erik A.
    Jensen, Thomas E.
    Sylow, Lykke
    JOURNAL OF PHYSIOLOGY-LONDON, 2018, 596 (12): : 2283 - 2299
  • [30] A role for kinesin in insulin-stimulated GLUT4 glucose transporter translocation in 3T3-L1 adipocytes
    Emoto, M
    Langille, SE
    Czech, MP
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (14) : 10677 - 10682